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005			20250625162455.0
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090			_aB-20780
245	1	0	_aBiosynthesis and biotechnological production of ginsenosides
490	0		_vBiotechnology advances, 33(6), p.717-735, 2015
520	3		_aMedicinal plants are essential for improving human health, and around 75 percent of the population in developing countries relies mainly on herb-based medicines for health care. As the king of herb plants, ginseng has been used for nearly 5000 years in the oriental and recently in western medicines. Among the compounds studied in ginseng plants, ginsenosides have been shown to have multiple medical effects such as anti-oxidative, anti-aging, anti-cancer, adaptogenic and other health-improving activities. Ginsenosides belong to a group of triterpene saponins (also called ginseng saponins)that are found almost exclusively in Panax species and accumulated especially in the plant roots. In this review, we update the conserved and diversified pathway/enzyme biosynthesizing ginsenosides which have been presented. Particularly, we highlight recent milestone works on functional characterization of key genes dedicated to the production of ginsenosides, and their application in engineering plants and yeast cells for large-scale production of ginsenosides.
650	1	4	_aPANAX
650	1	4	_aGINSENG
650	1	4	_aGINSENOSIDE
650	1	4	_aACCUMULTATION
650	1	4	_aBIOSYNTHESIS
650	1	4	_aPHYSIOLOGICAL ROLE
650	1	4	_aTRANSGENIC PLANTS
650	1	4	_aRECOMBINANT YEAST CELLS
650	1	4	_aINDUSTRIAL PRODUCTION
700	1	2	_aKim, Y. J.
700	1	2	_aZhang, D.
700	1	2	_aYang, D. C.
856	4	0	_uhttps://drive.google.com/file/d/1Fv8MPP6CUFdqbvKlYoVMp3S5WdXi5OuA/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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