000 02360nam a2200265Ia 4500
003 MX-MdCICY
005 20250625162458.0
040 _cCICY
090 _aB-20930
245 1 0 _aInvestigation of Phytochemical, Antioxidant and Antidiabetic Potentials of Scabiosa L.(Caprifoliaceae)Species with Chemometric Methods.
490 0 _vChemistry & BioDiversity, 21, p.e202301652, 2024
520 3 _aIn this research, the total phenolic and flavonoid amounts, phenolic compositions, in vitro antioxidant, antibacterial and antidiabetic properties of the methanol extracts obtained from Scabiosa L. (Caprifoliaceae)species distributed in the flora of Türkiye were investigated using chemometric methods. For this purpose, principal component (PCA)and agglomerative hierarchical clustering analysis were performed as chemometric methods. Chlorogenic acid, quinic acid and cyranoside were determined in the extracts. According to chemometric analysis, S. columbaria subsp. ochroleuca var. ochroleuca and S. triniifolia species were found to be valuable in terms of methanol extract yields, total phenolic and flavonoid contents, antioxidant and antidiabetic activities while S. columbaria subsp. ochroleuca var. webbiana species were found to be valuable in terms of phenolic composition. The methanol extracts of Scabiosa species showed high antioxidant activity, with high phenolic and flavonoid contents. Among the tested 13 bacteria, Scabiosa extracts showed only low activity against Klebsiella pneumoniae, Streptococcus pneumoniae and Pseudomonas aeruginosa. The extracts showed high ?-amylase and ?-glucosidase inhibitory activity. The results show that Scabiosa methanol extracts may be a source of alternative antioxidants that may be beneficial in slowing or preventing the progression of various oxidative stress-related diseases.
650 1 4 _aSCABIOSA L.
650 1 4 _aANTIBACTERIAL ACTIVITY
650 1 4 _aANTIDIABETIC ACTIVITY
650 1 4 _aANTIOXIDANT ACTIVITY
650 1 4 _aCHEMOMETRIC METHODS
700 1 2 _aAlbayrak, S.
700 1 2 _aAksoy, A.
700 1 2 _aYilmaz, M. A.
700 1 2 _aBeyzi, E.
856 4 0 _uhttps://drive.google.com/file/d/1AvRDrVIQRLixSHEfaRetnNGeDeUyEiyK/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
942 _2Loc
_cREF1
008 250602s9999 xx |||||s2 |||| ||und|d
999 _c55009
_d55009