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090 _aB-20939
245 1 0 _aA review of phototoxic plants, their phototoxic metabolites, and possible developments as photosensitizers
490 0 _vChemistry & BioDiversity, 21(2), p.e202300494, 2024
520 3 _aThis study provides a comprehensive overview of the current knowledge regarding phototoxic terrestrial plants and their phototoxic and photosensitizing metabolites. Within the 435,000 land plant species, only around 250 vascular plants have been documented as phototoxic or implicated in phototoxic occurrences in humans and animals. This work compiles a comprehensive catalog of these phototoxic plant species, organized alphabetically based on their taxonomic family. The dataset encompasses meticulous details including taxonomy, geographical distribution, vernacular names, and information on the nature and structure of their phototoxic and photosensitizing molecule(s). Subsequently, this study undertook an in-depth investigation into phototoxic molecules, resulting in the compilation of a comprehensive and up-to-date list of phytochemicals exhibiting phototoxic or photosensitizing activity synthesized by terrestrial plants. For each identified molecule, an extensive review was conducted, encompassing discussions on its phototoxic activity, chemical family, occurrence in plant families or species, distribution within different plant tissues and organs, as well as the biogeographical locations of the producer species worldwide. The analysis also includes a thorough discussion on the potential use of these molecules for the development of new photosensitizers that could be used in topical or injectable formulations for antimicrobial and anticancer phototherapy as well as manufacturing of photoactive devices.
650 1 4 _aNATURAL PRODUCT
650 1 4 _aPHOTODYNAMIC THERAPY
650 1 4 _aPHOTOSENSITIZER
650 1 4 _aPHOTOTOXICITY
650 1 4 _aPLANT
700 1 2 _aPetit, R.
700 1 2 _aIzambart, J.
700 1 2 _aGuillou, M.
700 1 2 _aDa Silva Almeida, J. R. G.
700 1 2 _aDe Oliveira Junior, R. G.
700 1 2 _aSol, V.
700 1 2 _aPicot, L.
856 4 0 _uhttps://drive.google.com/file/d/15TWvJfyDWHuaT1A4N6FC1SJxxZTutt7Z/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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