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245 1 0 _aHistone modification-dependent production of peptide hormones facilitates acquisition of pluripotency during leaf-to-callus transition in Arabidopsis
490 0 _vNew Phytologist, 10.1111/nph.19637, 2024
520 3 _aChromatin configuration is critical for establishing tissue identity and changes substantially during tissue identity transitions. The crucial scientific and agricultural technology of in vitro tissue culture exploits callus formation from diverse tissue explants and tissue regeneration via de novo organogenesis. We investigated the dynamic changes in H3ac and H3K4me3 histone modifications during leaf-to-callus transition in Arabidopsis thaliana. We analyzed changes in the global distribution of H3ac and H3K4me3 during the leaf-to-callus transition, focusing on transcriptionally active regions in calli relative to leaf explants, defined by increased accumulation of both H3ac and H3K4me3. Peptide signaling was particularly activated during callus formation; the peptide hormones RGF3, RGF8, PIP1 and PIPL3 were upregulated, promoting callus proliferation and conferring competence for de novo shoot organogenesis. The corresponding peptide receptors were also implicated in peptide-regulated callus proliferation and regeneration capacity. The effect of peptide hormones in plant regeneration is likely at least partly conserved in crop plants. Our results indicate that chromatin-dependent regulation of peptide hormone production not only stimulates callus proliferation but also establishes pluripotency, improving the overall efficiency of two-step regeneration in plant systems.
650 1 4 _aARABIDOPSIS THALIANA
650 1 4 _aCALLUS
650 1 4 _aPROLIFERATION
650 1 4 _aCHROMATIN LANDSCAPE
650 1 4 _aDE NOVO
650 1 4 _aSHOOT ORGANOGENESIS
650 1 4 _aPEPTIDE HORMONE
650 1 4 _aTWO-STEP PLANT REGENERATION
700 1 2 _aHong, C.
700 1 2 _aLee, H. G.
700 1 2 _aShim, S.
700 1 2 _aPark, O. S.
700 1 2 _aKim, J. H.
700 1 2 _aLee, K.
700 1 2 _aSeo, P. J.
856 4 0 _uhttps://drive.google.com/file/d/1CZw48ziS_5eDqgMIMPgfONm31BgiDZaw/view?usp=drivesdk
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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