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245 1 0 _aPromising role of emodin as therapeutics to against viral infections
490 0 _vFrontiers in Pharmacology, 13, 902626, 2022
520 3 _aEmodin is an anthraquinone derivative that is widely present in natural plants and has a wide spectrum of pharmacological effects, such as antibacterial, anti-inflammatory, anti-fibrotic and anticancer and so on. Through reviewing studies on antiviral effect of emodin in the past decades, we found that emodin exhibits ability of inhibiting the infection and replication of more than 10 viruses in vitro and in vivo, including herpes simplex virus type 1 (HSV-1)and type 2 (HSV-2), human cytomegalovirus (HCMV), Epstein-Barr virus (EBV), coxsackievirus B (CVB), hepatitis B virus (HBV), influenza A virus (IAV), SARS-CoV, viral haemorrhagic septicaemia rhabdovirus (VHSV), enterovirus 71 (EV71), dengue virus serotype 2 (DENV-2)and Zika virus (ZIKV). Therefore, this review aims to summarize the antiviral effect of emodin, in order to provide reference and hopes to support the further investigations.
650 1 4 _aEMODIN
650 1 4 _aVIRUS INFECTION
650 1 4 _aHSV-2
650 1 4 _aHCMV (HUMAN CYTOMEGALOVIRUS)
650 1 4 _aCOVID-19
700 1 2 _aShao, Q.
700 1 2 _aLiu, T.
700 1 2 _aWang, W.
700 1 2 _aLiu, T.
700 1 2 _aJin, X.
700 1 2 _aChen, Z.
856 4 0 _uhttps://drive.google.com/open?id=1xBA4ZT2x6PR-cJmvxpzlexZ6ECAD7Yvq&usp=drive_copy
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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