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003			MX-MdCICY
005			20250625162500.0
040			_cCICY
090			_aB-21059
245	1	0	_aTemperature and pH sensors based on graphenic materials
490	0		_vBiosensors and Bioelectronics, 91, p.870-877, 2017
520	3		_aPoint-of-care applications and patients' real-time monitoring outside a clinical setting would require disposable and durable sensors to provide better therapies and quality of life for patients. This paper describes the fabrication and performances of a temperature and a pH sensor on a biocompatible and wearable board for healthcare applications. The temperature sensor was based on a reduced graphene oxide (rGO)layer that changed its electrical resistivity with the temperature. When tested in a human serum sample between 25 and 43 °C, the sensor had a sensitivity of 110±10 ?/°C and an error of 0.4±0.1 °C compared with the reference value set in a thermostatic bath. The pH sensor, based on a graphene oxide (GO)sensitive layer, had a sensitivity of 40±4 mV/pH in the pH range between 4 and 10. Five sensor prototypes were tested in a human serum sample over one week and the maximum deviation of the average response from reference values obtained by a glass electrode was 0.2 pH units. For biological applications, the temperature and pH sensors were successfully tested for in vitro cytotoxicity with human fibroblast cells (MRC-5)over 24 h.
650	1	4	_aPH
650	1	4	_aTEMPERATURE
650	1	4	_aGRAPHENE
650	1	4	_aFLEXIBLE SENSOR
700	1	2	_aSalvo, P.
700	1	2	_aCalisi, N.
700	1	2	_aMelai, B.
700	1	2	_aCortigiani, B.
700	1	2	_aMannini, M.
700	1	2	_aCaneschi, A.
700	1	2	_aDi Francesco, F.
856	4	0	_uhttps://drive.google.com/open?id=1iLkF2FZ_bNgSa24_It6R-EexhVlZ0nVr&usp=drive_copy _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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