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245 1 0 _aCEPs suppress auxin signaling but promote cytokinin signaling to inhibit root growth in Arabidopsis
490 0 _vBioChemical and Biophysical Research Communications, 711, p.149934, 2024
520 3 _aC-terminally encoded peptides (CEPs)are peptide hormones that function as mobile signals coordinating crucial developmental programs in plants. Previous studies have revealed that CEPs exert negative regulation on root development through interaction with CEP receptors (CEPRs), CEP DOWNSTREAMs (CEPDs), the cytokinin receptor ARABIDOPSIS HISTIDINE KINASE (AHKs)and the transcriptional repressor Auxin/Indole-3-Acetic Acid (AUX/IAA). However, the precise molecular mechanisms underlying CEPs-mediated regulation of root development via auxin and cytokinin signaling pathways still necessitate further detailed investigation. In this study, we examined prior research and elucidated the underlying molecular mechanisms. The results showed that both synthetic AtCEPs and overexpression of AtCEP5 markedly supressed primary root elongation and lateral root (LR)formation in Arabidopsis. Molecular biology and genetics elucidated how CEPs inhibit root growth by suppressing auxin signaling while promoting cytokinin signaling. In summary, this study elucidated the inhibitory effects of AtCEPs on Arabidopsis root growth and provided insights into their potential molecular mechanisms, thus enhancing our comprehension of CEP-mediated regulation of plant growth and development.
650 1 4 _aARABIDOPSIS (ARABIDOPSIS THALIANA)
650 1 4 _aAUXIN
650 1 4 _aCEP
650 1 4 _aCYTOKININ
650 1 4 _aROOT DEVELOPMENT
700 1 2 _aZhang, Y.
700 1 2 _aDuan, X.
700 1 2 _aWang, Z.
700 1 2 _aLv, Y.
700 1 2 _aQi, W.
700 1 2 _aLi, L.
700 1 2 _aXuan, W.
856 4 0 _uhttps://drive.google.com/open?id=1uSF7A1wv529I0TlPfCFw35TJWLwpcib6&usp=drive_copy
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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