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245 1 0 _aLactones. 6. Microbial lactonization of gamma,delta-epoxy esters
490 0 _vChirality: The Pharmacological, Biological, and Chemical Consequences of Molecular Asymmetry, 13(6), p.302-307, 2001
520 3 _aThe ability of 19 microorganisms to perform the enantioselective lactonization of racemic gamma,delta-epoxy ester 3a and its 7-methyl homolog 3b was checked. It was found that Rhodotorula rubra preferentialy transformed both substrates to (-)-enantiomers of trans delta-hydroxy-gamma-lactones with ee 76 percent for 3a and 24 percent for 3b. The best efficiency (20-30 percent)and enantioselectivity (ee 60-100 percent)of formation of (-)-gamma-hydroxy-delta-lactones 6a and 6b was observed for lactonization by Botrytis cinerea and Fusarium semitectum, respectively.
650 1 4 _aTERPENOID LACTONES
650 1 4 _aBIOCATALYSTS
650 1 4 _aSHARPLESS EPOXIDATION
650 1 4 _aMICROORGANISMS
650 1 4 _aRHODOTORULA RUBRA
650 1 4 _aBOTRYTIS CINEREA
650 1 4 _aFUSARIUM SEMITECTUM
700 1 2 _aOlejniczak, T.
700 1 2 _aGawronski, J.
700 1 2 _aWawrzenczyk, C.
856 4 0 _uhttps://drive.google.com/open?id=1hqan1LskkJmXUxH2Hr8tH6D73akBEddM&usp=drive_copy
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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