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090			_aB-21236
245	1	0	_aDelivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles
490	0		_aBiomaterials Science. 7(8), 3138-3142, 2019, DOI: 10.1039/c9bm00785g
520	3		_aWhile highly promising in medicine, gene therapy requires delivery agents to protect and target nucleic acid therapeutics. We developed a plant viral siRNA delivery platform making use of self-assembling cowpea chlorotic mottle virus (CCMV). CCMV was loaded with siRNAs targeting GFP or FOXA1; to further enhance cell uptake and intracellular trafficking, resulting in more efficient gene knockdown, we appended CCMV with a cell penetrating peptide (CPP), specifically M-lycotoxin peptide L17E. © 2019 The Royal Society of Chemistry.
700	1	2	_aLam P.
700	1	2	_aSteinmetz N.F.
856	4	0	_uhttps://drive.google.com/file/d/1JnRlUyw5qQ21MxFH7Bx4guXgG04Jhj3S/view?usp=drivesdk _zPara ver el documento ingresa a Google con tu cuenta @cicy.edu.mx
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