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245 1 0 _aMalate dehydrogenase in plants: evolution, structure, and a myriad of functions
490 0 _aEssays in Biochemistry, 13, p.EBC20230089, 2024
500 _aArtículo
520 3 _aMalate dehydrogenase (MDH) catalyzes the interconversion of oxaloacetate and malate coupled to the oxidation/reduction of coenzymes NAD(P)H/NAD(P)+. While most animals have two isoforms of MDH located in the cytosol and mitochondria, all major groups of land plants have at least six MDHs localized to the cytosol, mitochondria, plastids, and peroxisomes. This family of enzymes participates in important reactions in plant cells including photosynthesis, photorespiration, lipid metabolism, and NH4 + metabolism. MDH also helps to regulate the energy balance in the cell and may help the plant cope with various environmental stresses. Despite their functional diversity, all of the plant MDH enzymes share a similar structural fold and act as dimers. In this review, we will introduce readers to our current understanding of the plant MDHs, including their evolution, structure, and function. The focus will be on the MDH enzymes of the model plant Arabidopsis thaliana.
650 1 4 _aARABIDOPSIS
650 1 4 _aEVOLUTION
650 1 4 _aMOLECULAR
650 1 4 _aMALATE DEHYDROGENASE
650 1 4 _aPLANTS
700 1 2 _aBaird, L. M.
700 1 2 _aBerndsen, C. E.
700 1 2 _aMonroe, J. D.
856 4 0 _uhttps://drive.google.com/file/d/10gWeji3OIV2OAHpyt8ea5q0BLNMP5OWA/view?usp=drive_link
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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