000			02946nam a2200313Ia 4500
003			MX-MdCICY
005			20250626080925.0
040			_cCICY
090			_aB-19455
245	1	0	_aChromosome-level de novo genome assembly and whole-genome resequencing of the threatened species Acanthochlamys bracteata (Velloziaceae) provide insights into alpine plant divergence in a biodiversity hotspot
490	0		_aMolecular Ecology Resources, 22(4), p.1582-1595, 2022
500			_aArtículo
520	3		_aThe Hengduan Mountains region is an important hotspot of alpine plant diversity and endemism. Acanthochlamys bracteata is a species of a threatened monotypic genus endemic to the Hengduan Mountains. In this study, we present a high-quality, chromosome-level reference genome for A. bracteata, constructed using long reads, short reads and Hi-C technology. We characterized its genetic diversity, population structure, demographic history and gene flow by resequencing individuals collected across its distribution. Comparative genomics analyses based on sequence information from single-copy orthologous genes revealed that A. bracteata and Dioscorea rotundata diverged ~104.5 million years ago. Whole-genome resequencing based on population genetic analysis revealed that the division of the 14 populations into 10 distinct clusters reflected geographical divergence, and three separate high levels of gene flow occurred sequentially between isolated populations of the Hengduan Mountains, a finding which is consistent with the turnover between ice ages and interglacial periods. Our findings indicate that Quaternary climatic changes played an important role in shaping the genetic structure and demographic trajectories of A. bracteata, and provide critical insights into the genetic status and evolutionary history of this poorly understood species, and possibly other alpine plants with a similar distribution. This study demonstrates the usefulness of population genomics for evaluating the effects of past climatic changes and identifying conservation units for the conservation and management of threatened species. Our high-quality genome represents a valuable resource for future studies of the underlying molecular mechanisms of adaptive evolution and provides insight for further comparative genomic analysis with other Velloziaceae species.
650	1	4	_aACANTHOCHLAMYS BRACTEATA
650	1	4	_aGENE FLOW
650	1	4	_aHI-C
650	1	4	_aPOPULATION GENOMICS
650	1	4	_aTHREATENED SPECIES
700	1	2	_aXu, B.
700	1	2	_aLiao, M.
700	1	2	_aDeng, H. N.
700	1	2	_aYan, C. C.
700	1	2	_aLv, Y. Y.
700	1	2	_aGao, Y. D.
700	1	2	_aGao, X. F.
856	4	0	_uhttps://drive.google.com/file/d/1maACmQqY2KWv3BUkiQhocbs_s3nt_dcd/view?usp=drive_link _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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