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245 1 0 _aThe Trypanosoma cruzi proteome
490 0 _aScience, 309(5733), p.473-476, 2005
520 3 _aTo complement the sequencing of the three kinetoplastid genomes reported in this issue, we have undertaken a whole-organism, proteomic analysis of the four life-cycle stages of Trypanosoma cruzi. Peptides mapping to 2784 proteins in 1168 protein groups from the annotated T. cruzi genome were identified across the four life-cycle stages. Protein products were identified from >1000 genes annotated as "hypothetical" in the sequenced genome, including members of a newly defined gene family annotated as mucin-associated surface proteins. The four parasite stages appear to use distinct energy sources, including histidine for stages present in the insect vectors and fatty acids by intracellular amastigotes.
700 1 2 _aAtwood III, J. A.
700 1 2 _aWeatherly, D. B.
700 1 2 _aMinning, T. A.
700 1 2 _aBundy, B.
700 1 2 _aCavola, C.
700 1 2 _aOpperdoes, F. R.
700 1 2 _aTarleton, R. L.
856 4 0 _uhttps://drive.google.com/file/d/1n3_n9Yg5DKYqXo0wzVQPdeKYQXvj-DG3/view?usp=drive_link
_zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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