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090			_aB-21614
245	1	0	_aPathogen perception by NLRs in plants and animals: Parallel worlds
490	0		_aBioEssays, 38(8), p.769-781, 2016
500			_aArtículo
520	3		_aIntracellular NLR (Nucleotide-binding domain and Leucine-rich Repeat-containing) receptors are sensitive monitors that detect pathogen invasion of both plant and animal cells. NLRs confer recognition of diverse molecules associated with pathogen invasion. NLRs must exhibit strict intramolecular controls to avoid harmful ectopic activation in the absence of pathogens. Recent discoveries have elucidated the assembly and structure of oligomeric NLR signalling complexes in animals, and provided insights into how these complexes act as scaffolds for signal transduction. In plants, recent advances have provided novel insights into signalling-competent NLRs, and into the myriad strategies that diverse plant NLRs use to recognise pathogens. Here, we review recent insights into the NLR biology of both animals and plants. By assessing commonalities and differences between kingdoms, we are able to develop a more complete understanding of NLR function.
650	1	4	_aANIMALS
650	1	4	_aEFFECTORS
650	1	4	_aINNATE IMMUNITY
650	1	4	_aNLR
650	1	4	_aPLANTS
650	1	4	_aRECEPTORS
700	1	2	_aDuxbury, Z.
700	1	2	_aMa, Y.
700	1	2	_aFurzer, O. J.
700	1	2	_aHuh, S. U.
700	1	2	_aCevik, V.
700	1	2	_aJones, J. D.
700	1	2	_aSarris, P. F.
856	4	0	_uhttps://drive.google.com/file/d/14ydo8H9tdyth3qvfMy9XkLICi7VQ4wgb/view?usp=drive_link _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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