000			02176nam a2200289Ia 4500
003			MX-MdCICY
005			20250626090916.0
040			_cCICY
090			_aB-21709
245	1	0	_aHeterotrophic cultivation of microalgae: production of metabolites of commercial interest
490	0		_aJournal of Chemical Technology & Biotechnology, 92, p.925-936, 2017
500			_aArtículo
520	3		_aSeveralmicroalgal species are capable of growing heterotrophically, exhibiting considerablemetabolic versatility and flexibility. As demonstrated in this review, heterotrophic conditions can enhance the biomass concentration by as much as 25-fold compared with phototrophic conditions. Currently, these types of cultivation are economically feasible only for high-value products, including polyunsaturated fatty acids (PUFAs), pigments, antioxidants, polysaccharides, food and aquaculture feed from carbon sources, such as glucose, acetate or glycerol. To make heterotrophic cultivation economically viable for high-volume, low-value commodities, such as biofuels, the use of unconventional carbon sources, such as food and agricultural wastes and wastewater, is recommended. Since microalgae are capable of modifying their metabolism according to varying culture conditions, it is possible to modify, control and therefore maximize the production of target compounds. This manuscript not only offers a review of the most relevant and recent findings in the use of heterotrophic microalgal cultivation for enhanced metabolite production but also provides recommendations for future research on this promising subject.
650	1	4	_aMICROALGAE
650	1	4	_aHETEROTROPHIC GROWTH
650	1	4	_aCARBON SOURCES
650	1	4	_aLIPIDS
650	1	4	_aPOLYUNSATURATED FATTY ACIDS
650	1	4	_aPIGMENTS
650	1	4	_aBIODIESEL
700	1	2	_aMorales‐Sánchez, D.
700	1	2	_aMartinez‐Rodriguez, O. A.
700	1	2	_aMartinez, A.
856	4	0	_uhttps://drive.google.com/file/d/1B95_U2SJ_lWWYkbl1VN1VzJzxkrbyZQD/view?usp=drive_link _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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