000			03308nam a22004335i 4500
001			978-0-306-48644-9
003			DE-He213
005			20260127103410.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9780306486449
020			_a99780306486449
024	7		_a10.1007/b111738 _2doi
040			_cCICY
082	0	4	_a612.8 _223
100	1		_aGill, Santokh. _eeditor.
245	1	0	_aGlutamate Receptors in Peripheral Tissue: Excitatory Transmission Outside the CNS _h[recurso electrónico] / _cedited by Santokh Gill, Olga Pulido.
264		1	_aBoston, MA : _bSpringer US, _c2005.
300			_aXIV, 270 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aGeneral Concepts -- Glutamate Receptors in Peripheral Tissues: Distribution and Implications for Toxicology -- Glutamate Receptor Pharmacology: Lessons Learned from the Last Decade of Stroke Trials -- Expression of Non-Organelle Glutamate Transporters to Support Peripheral Tissue Function -- Anticancer Effects of Glutamate Antagonists -- Glutamate Receptors and their Role in Acute and Inflammatory Pain -- Specific Target Tissues, Organs, and Systems -- The Vertebrate Retina -- Glutamate Receptors in Taste Receptor Cells -- Glutamate Receptors in Endocrine Tissues -- Adrenal Glutamate Receptors: A Role in Stress and Drug Addiction? -- Glutamate Receptors in the Stomach and their Implications -- Glutamate Toxicity in Lung and Airway Disease -- Glutamate: Teaching Old Bones New Tricks-Implications for Skeletal Biology -- Expression and Function of Metabotropic Glutamate Receptors in Liver -- Neuroexcitatory Signaling in Immune Tissues -- Platelet Glutamate Receptors as a Window into Psychiatric Disorders -- Non-Mammalian Organisms -- Analysis of Glutamate Receptor Genes in Plants: Progress and Prospects.
520			_aWhen the brain suffers an injury such as a stroke, neurons release glutamate onto nearby neurons which become excited, overloaded with calcium, and die. Normal neurotransmission is altered during injury, causing excess calcium to activate enzymes which eventually leads to destruction of the cell. This damage occurs through glutamate receptors. At one time, glutamate receptors were thought to exist exclusively in the CNS. It is only recently that they have been found outside the CNS, in the peripheral tissue. The editors of Glutamate Receptors in Peripheral Tissue: Excitatory Transmission Outside the CNS are the first to show their presence outside the CNS using molecular biology techniques and immunohistochemistry. This text is the first devoted exclusively to these receptors in peripheral tissues.
650		0	_aMEDICINE.
650		0	_aNEUROSCIENCES.
650		0	_aNEUROLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aNEUROSCIENCES.
650	2	4	_aNEUROLOGY.
700	1		_aPulido, Olga. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780306479731
856	4	0	_uhttp://dx.doi.org/10.1007/b111738 _zVer el texto completo en las instalaciones del CICY
942			_2ddc _cER
999			_c55889 _d55889