000 04235nam a22004575i 4500
001 978-0-387-09693-3
003 DE-He213
005 20250710083924.0
007 cr nn 008mamaa
008 100301s2009 xxu| s |||| 0|eng d
020 _a9780387096933
_a99780387096933
024 7 _a10.1007/978-0-387-09693-3
_2doi
082 0 4 _a612.8
_223
100 1 _aFarooqui, Akhlaq.
_eauthor.
245 1 0 _aHot Topics in Neural Membrane Lipidology
_h[recurso electrónico] /
_cby Akhlaq Farooqui.
264 1 _aNew York, NY :
_bSpringer US,
_c2009.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aNeural Membranes: A Pandora's Box of Lipid Mediators -- Interplay Among Glycerophospholipid, Sphingolipid, and Cholesterol-Derived Lipid Mediators in Brain: A Matter of Life and Death -- Janus Face of Phospholipase A2: Role of Phospholipase A2 in Neural Cell Survival and Death -- Glycerophospholipid Metabolism in the Nucleus: Cross Talk Among Phospholipase A2, Phospholipase C and Phospholipase D -- Ether Glycerophospholipids: The Workhorse Lipids of Neural Membranes -- Excitotoxicity-Mediated Neurochemical Changes in Neurological Disorders -- Recent Developments on Kainate-Mediated Neurotoxicity and Their Association with Generation of Lipid Mediators -- Beneficial Effects of Docosahexaenoic Acid on Health of the Human Brain -- Effects of Statins and n-3 Fatty Acids on Heart and Brain Tissues: The Clash of the Titans -- Apoptosis and Necrosis in Brain: Contribution of Glycerophospholipid, Sphingolipid, and Cholesterol-Derived Lipid Mediators -- Perspective and Directions for Future Developments on Glycerophospholipid-, Sphingolipid-, and Cholesterol-Derived Lipid Mediators.
520 _aNot only do glycerophospholipid, sphingolipid, and cholesterol-derived lipid mediators facilitate the transfer of messages from one cell to another, they also facilitate communication among subcellular organelles. Hot Topics in Neural Membrane Lipidology provides readers with a cutting-edge, comprehensive review of these lipid mediators, their roles and association with neurological disorders, and the future direction of research on the topic. This monograph provides readers with critical data and is particularly accessible to neuroscience graduate students, teachers, and researchers. It can be used as a supplemental text for a range of neuroscience courses. Clinicians and pharmacologists will find this book useful for understanding molecular aspects of lipid mediators in acute neural trauma like stroke, spinal cord trauma, head injury, and neurodegenerative diseases such as Alzheimer disease, Parkinson disease, and Huntington disease. About the Author: Akhlaq A. Farooqui is a leader in the field of brain phospholipases A2, bioactive ether lipid metabolism, and glutamate-mediated neurotoxicity. He has discovered the stimulation of plasmalogen-selective phospholipase A2 activity in brains from patients with Alzheimer disease, and published cutting edge research on the generation and identification of glycerophospholipid, sphingolipid, and cholesterol-derived lipid mediators in kainic acid neurotoxicity. Dr. Farooqui has authored three monographs: Glycerophospholipids in Brain: Phospholipase A2 in Neurological Disorders (2007); Neurochemical Aspects of Excitotoxicity (2008); and Metabolism and Functions of Bioactive Ether Lipids in Brain (2008). All monographs are published by Springer, New York.
650 0 _aMEDICINE.
650 0 _aNEUROSCIENCES.
650 0 _aNEUROCHEMISTRY.
650 0 _aNEUROLOGY.
650 0 _aPSYCHOPHARMACOLOGY.
650 1 4 _aBIOMEDICINE.
650 2 4 _aNEUROSCIENCES.
650 2 4 _aNEUROCHEMISTRY.
650 2 4 _aNEUROLOGY.
650 2 4 _aPSYCHOPHARMACOLOGY.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387096926
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-09693-3
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c56029
_d56029