000 04417nam a22005055i 4500
001 978-0-387-09846-3
003 DE-He213
005 20250710083926.0
007 cr nn 008mamaa
008 100301s2009 xxu| s |||| 0|eng d
020 _a9780387098463
_a99780387098463
024 7 _a10.1007/978-0-387-09846-3
_2doi
082 0 4 _a571.8
_223
100 1 _aHall, Brian K.
_eeditor.
245 1 4 _aThe Neural Crest and Neural Crest Cells in Vertebrate Development and Evolution
_h[recurso electrónico] /
_cedited by Brian K. Hall.
264 1 _aBoston, MA :
_bSpringer US,
_c2009.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aDiscovery and Origins -- Discovery -- Embryological Origins and the Identification of Neural Crest Cells -- Delamination, Migration, and Potential -- Evolutionary Origins -- Neural-Crest Derivatives -- Pigment Cells (Chromatophores) -- Neuronal Cells and Nervous Systems -- Cartilage Cells and Skeletal Systems -- Teeth and Hearts: The Odontogenic and Cardiac Neural Crests -- Abnormal Development and the Neural Crest -- Neurocristopathies -- NCC Development Revisited in the Context of Birth Defects.
520 _aThe evolution of the neural crest sheds light on many of the oldest unanswered questions in developmental biology, including the role of germ layers in early embryogenesis, the development of the nervous system, how the vertebrate head arose developmentally and evolutionarily, and how growth factors and Hox genes direct cell differentiation and embryonic patterning. In this new edition of his essential work, The Neural Crest in Development and Evolution, Brian Hall has provided an up-to-date technically and intellectually rigorous synthesis of knowledge of all aspects of the neural crest and of neural crest cells (NCCs). These ten chapters are organized into three parts: (I) The discovery, and developmental and evolutionary origins of the neural crest; (II) cellular and tissue derivatives of the neural crest; (III) and tumors and birth defects arising from abnormal NCCs. The genetic and cellular bases for the identification of NCCs as early as during gastrulation, for induction of the neural crest, NCC delamination, migration and differentiation - understanding of all of which has increased enormously over the past decade - are discussed in depth in Part I. The evolutionary origin(s) of the neural crest is examined through an analysis of fossils, and of cell types, genes and gene networks in extant cephalochordates (amphioxus) and in ascidians. Four chapters grouped as Part II examine all aspects of neural crest-derived pigment cells, neurons, skeletal, cardiac and tooth-forming cells, with emphasis on how and when subpopulations of NCCs are specified and how their differentiation is controlled. The two chapters in Part III revisit NCC development in the context of tumors (neurocristopathies) and birth defects, with emphasis on genetic pathways, regulation of cell populations, and whether NCCs can be considered to be stem cells. About the Author: About the Author: Dr. Brian K. Hall has devoted much of his career to the study of the evolution and development of neural crest-derived skeletal tissues. He is a University Research Professor Emeritus at Dalhousie University in Halifax, Canada, a Visiting Distinguished Professor at Arizona State University in Tempe, a Fellow of the Royal Society of Canada, and a foreign fellow of the American Academy of Arts and Sciences.
650 0 _aLIFE SCIENCES.
650 0 _aHUMAN GENETICS.
650 0 _aCYTOLOGY.
650 0 _aDEVELOPMENTAL BIOLOGY.
650 0 _aEVOLUTION (BIOLOGY).
650 0 _aNEUROBIOLOGY.
650 0 _aANTHROPOLOGY.
650 1 4 _aLIFE SCIENCES.
650 2 4 _aDEVELOPMENTAL BIOLOGY.
650 2 4 _aEVOLUTIONARY BIOLOGY.
650 2 4 _aNEUROBIOLOGY.
650 2 4 _aCELL BIOLOGY.
650 2 4 _aHUMAN GENETICS.
650 2 4 _aANTHROPOLOGY.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387098456
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-09846-3
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c56088
_d56088