000			03472nam a22004455i 4500
001			978-0-387-23101-3
003			DE-He213
005			20250710083927.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9780387231013 _a99780387231013
024	7		_a10.1007/b100628 _2doi
082	0	4	_a572 _223
100	1		_aLendeckel, Uwe. _eeditor.
245	1	0	_aProteases In The Brain _h[recurso electrónico] / _cedited by Uwe Lendeckel, Nigel M. Hooper.
264		1	_aBoston, MA : _bSpringer US, _c2005.
300			_aXVI, 383 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aProteases In Biology and Disease ; _v3
505	0		_aProteases and Alzheimer's Disease: Present Knowledge and Emerging Concepts of Therapy -- Calpain Proteolysis and the Etiology of Parkinson's Disease: An Emerging Hypothesis -- Cysteine Proteases in Neuronal Death in Brain Ischemia -- Proteases in Traumatic Brain Injury -- Proteases in CNS Infection and Inflammation -- Dipeptidyl Peptidase IV Regulates T Cell Function in CNS Inflammation -- Role and Regulation of Proteases in Human Glioma -- Proteases and Prion Diseases -- Neuropeptide Processing -- Proteases and Neuronal Plasticity -- Serine Proteases and Neuronal Plasticity in vivo -- Proteases and Synaptic Activity -- Role of Proteinase-Activated Receptors in Brain Function -- Matrix Metalloproteinases and Neuroinflammation in Multiple Sclerosis.
520			_aIn all organs of the body proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer's, Parkinson's and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumour progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes. Proteases in the Brain reviews the role and regulation of proteases in Alzheimer's disease brain ischemia and traumatic brain injury human glioma inflammatory and infectious diseases of the central nervous system metabolism of the prion protein modulating synaptic activity multiple sclerosis neuronal plasticity and memory consolidation Parkinson's disease processing, conversion and inactivation of neuropeptides. Proteases in the Brain is a timely and useful source of information both for those well versed in the role of proteases in the brain and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.
650		0	_aLIFE SCIENCES.
650		0	_aNEUROSCIENCES.
650		0	_aBIOCHEMISTRY.
650	1	4	_aLIFE SCIENCES.
650	2	4	_aBIOCHEMISTRY, GENERAL.
650	2	4	_aNEUROSCIENCES.
700	1		_aHooper, Nigel M. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387231006
830		0	_aProteases In Biology and Disease ; _v3
856	4	0	_uhttp://dx.doi.org/10.1007/b100628 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c56139 _d56139