000			03387nam a22004335i 4500
001			978-0-387-24361-0
003			DE-He213
005			20250710083931.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9780387243610 _a99780387243610
024	7		_a10.1007/b105234 _2doi
082	0	4	_a616.994 _223
100	1		_aPlatanias, Leonidas C. _eeditor.
245	1	0	_aCytokines and Cancer _h[recurso electrónico] / _cedited by Leonidas C. Platanias.
264		1	_aBoston, MA : _bSpringer US, _c2005.
300			_aXVI, 377 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCancer Treatment and Research, _x0927-3042 ; _v126
505	0		_aBasic Science Research -- Polypeptide Growth Factors and Their Receptors -- Chemokines and Cancer -- Interferons -- Cytokines and Lymphomas -- Pro-apototic and Anti-apoptotic Effects of Tumor Necrosis Factor in Tumor Cells -- Transforming Growth Factor Beta and Breast Cancer -- Transforming Growth Factor Beta and Prostate Cancer -- Angiostatin -- Clinical and Translational Research -- Interferons in the Treatment of Solid Tumors -- Targeting Cytokine Receptors and Pathways in the Treatment of Breast Cancer -- Interleukin-2 in the Treatment of Renal Cell Carcinoma and Malignant Melanoma -- Cytokine Targeted Treatments for Lung Cancer -- Cytokines in the Treatment of Acute Leukemias -- Cytokines in Hematopoietic Stem Cell Transplantation -- Novel Cytokines in the Treatment of Malignancies.
520			_aThis volume provides a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies. To date, there has not been a book published that covers both basic science and translational/clinical research in the field of cytokines in malignancies. The volume is divided in two sections. Section one focuses on current developments in the basic science field with particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second section deals with translational and clinical research in the field, and many of the chapter authors were among the first to introduce several cytokines in the treatment of certain tumors. Cytokines and Cancer is written by leading figures in the field of cytokine biology and cytokine therapeutics and is specifically focused on this subject. Collectively, the information provided in this book will be helpful to people in the medical field at several levels, including medical students, interns, residents, clinical and basic science researchers, as well as oncologists in practice.
650		0	_aMEDICINE.
650		0	_aHEMATOLOGY.
650		0	_aONCOLOGY.
650	1	4	_aMEDICINE & PUBLIC HEALTH.
650	2	4	_aONCOLOGY.
650	2	4	_aHEMATOLOGY.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387243603
830		0	_aCancer Treatment and Research, _x0927-3042 ; _v126
856	4	0	_uhttp://dx.doi.org/10.1007/b105234 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SME
942			_2ddc _cER
999			_c56343 _d56343