000 02878nam a22004095i 4500
001 978-0-387-25575-0
003 DE-He213
005 20250710083933.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387255750
_a99780387255750
024 7 _a10.1007/b135603
_2doi
082 0 4 _a616.12
_223
100 1 _aMarín-García, José.
_eeditor.
245 1 0 _aMitochondria and the Heart
_h[recurso electrónico] /
_cedited by José Marín-García.
264 1 _aBoston, MA :
_bSpringer US,
_c2005.
300 _aXVIII, 400 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aDevelopments in Cardiovascular Medicine,
_x0166-9842 ;
_v256
505 0 _aAn Introduction to Mitochondria and the Heart -- Mitochondrial Bioenergetics in the Heart -- Heart Mitochondrial Biogenesis -- ROS Generation, Antioxidants, and Cell Death -- Myocardial Ischemia and Cardioprotection -- Mitochondria Dysfunction in Cardiomyopathy and Heart Failure -- Fatty Acid and Glucose Metabolism in Cardiac Disease -- Mitochondria in Pediatric Cardiology -- Mitochondria and the Aging Heart -- Heart Mitochondria Signaling Pathways -- Treatment of Mitochondrial-Based Cardiac Diseases. Targeting the Organelle -- Future Frontiers in Mitochondrial Cardiac Biology.
520 _aThe function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases. José Marín-García is affiliated with The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey and the Department of Physiology & Biophysics, UMDNJ - Robert Wood Johnson Medical School, Piscataway, New Jersey.
650 0 _aMEDICINE.
650 0 _aCARDIOLOGY.
650 1 4 _aMEDICINE & PUBLIC HEALTH.
650 2 4 _aCARDIOLOGY.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387255743
830 0 _aDevelopments in Cardiovascular Medicine,
_x0166-9842 ;
_v256
856 4 0 _uhttp://dx.doi.org/10.1007/b135603
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SME
942 _2ddc
_cER
999 _c56451
_d56451