000 03021nam a22003975i 4500
001 978-0-387-26476-9
003 DE-He213
005 20250710083936.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387264769
_a99780387264769
024 7 _a10.1007/b137670
_2doi
082 0 4 _a611.01816
_223
100 1 _aRazzaque, Mohammed S.
_eauthor.
245 1 0 _aFibrogenesis: Cellular and Molecular Basis
_h[recurso electrónico] /
_cby Mohammed S. Razzaque.
264 1 _aBoston, MA :
_bSpringer US,
_c2005.
300 _aApprox. 230 p. 44 illus., 3 in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMedical Intelligence Unit
505 0 _aTissue Scarring -- Pathological Significance of Renal Expression of Proinflammatory Molecules -- Oxidative Stress, Lipoproteins and Angiotensin II -- Involvement of NF-?B in Renal Inflammation and Sclerosis -- Low-Denisty Lipoprotein and Glomerulosclerosis -- Molecular Developments in the Treatment of Renal Fibrosis -- Myocardial Infarction and Cardiac Fibrogenesis -- Cardiac Fibrosis and Aging -- Matrix Remodeling and Atherosclerosis Effect of Age -- Molecular and Cellular Aspects of Liver Fibrosis -- Recent Therapeutic Developments in Hepatic Fibrosis -- Reversibility of Liver Fibrosis -- Can Manipulation of Apoptotic Cell Death Benefit Tissue Scarring? -- Pulmonary Fibrogenesis -- Silica-Induced Inflammatory Mediators and Pulmonary Fibrosis.
520 _aFibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options. The chapters in this book have been selected to provide comprehensive information on fibrogenesis, which is not limited to any specific organ. Individual chapters present mechanisms of fibrotic diseases involving lung, liver, kidney, heart, blood vessels, and more. The relevance and significance of inflammatory cytokines, chemokines, transcriptional factors, fibrogenic molecules, signaling cascade, and matrix remodeling in fibrogenesis are explained in depth, providing the reader with current and updated information.
650 0 _aMEDICINE.
650 1 4 _aBIOMEDICINE.
650 2 4 _aMOLECULAR MEDICINE.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780306478611
830 0 _aMedical Intelligence Unit
856 4 0 _uhttp://dx.doi.org/10.1007/b137670
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c56578
_d56578