000 03804nam a22005295i 4500
001 978-0-387-27526-0
003 DE-He213
005 20250710083938.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387275260
_a99780387275260
024 7 _a10.1007/0-387-27526-6
_2doi
082 0 4 _a571.6
_223
100 1 _aZamponi, Gerald W.
_eauthor.
245 1 0 _aVoltage-Gated Calcium Channels
_h[recurso electrónico] /
_cby Gerald W. Zamponi.
264 1 _aBoston, MA :
_bSpringer US,
_c2005.
300 _aXIV, 377 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _arecurso en línea
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMolecular Biology Intelligence Unit
505 0 _aCa2+ Chemistry, Storage and Transport in Biologic Systems -- Monitoring Intracellular Ca2+ in Brain Slices with Fluorescent Indicators -- A Brief History of Calcium Channel Discovery -- Biochemical Studies of Voltage-Gated Ca2+ Channels -- Molecular Properties of Voltage-Gated Calcium Channels -- Role of ? Subunits in Voltage-Gated Calcium Channel Functions -- Distribution and Targeting Mechanisms of Voltage Activated Ca2+ Channels -- The Calcium Channel and the Transmitter Release Site -- Determinants of G Protein Inhibition of Presynaptic Calcium Channels -- Phosphorylation-Dependent Regulation of Voltage-Gated Ca2+ Channels -- Ca2+-Dependent Modulation of Voltage-Gated Ca2+ Channels -- Voltage-Dependent Inactivation of Voltage Gated Calcium Channels -- Selective Permeability of Voltage-Gated Calcium Channels -- The Run-Down Phenomenon of Ca2+ Channels -- Calcium Channels As Therapeutic Targets -- Calcium Channelopathies -- The Molecular Basis of Ca2+ Antagonist Drug Action-Recent Developments -- Calcium Channel Block and Inactivation -- Block of Voltage-Gated Calcium Channels by Peptide Toxins -- Calcium Channels in the Heart -- Post-Genomic Insights into T-Type Calcium Channel Functions in Neurons -- Voltage-Gated Ca2+ Channels of the Vertebrate Retina -- Exploring the Function and Pharmacotherapeutic of Potential Voltage-Gated Ca2+ Channels with Gene-Knockout Models.
520 _aVoltage Gated Calcium Channels is the first comprehensive book in the calcium channel field, encompassing over thirty years of progress towards our understanding of calcium channel structure, function, regulation, physiology, pharmacology, and genetics. This book balances contributions from many of the leading authorities in the calcium channel field with fresh perspectives from risings stars in the area, taking into account the most recent literature and concepts. This is the only all-encompassing calcium channel book currently available, and is an essential resource for academic researchers at all levels in the areas neuroscience, biophysics, and cardiovascular sciences, as well as to researchers in the drug discovery area.
650 0 _aLIFE SCIENCES.
650 0 _aHUMAN PHYSIOLOGY.
650 0 _aNEUROSCIENCES.
650 0 _aTOXICOLOGY.
650 0 _aCARDIOLOGY.
650 0 _aCYTOLOGY.
650 0 _aBIOMEDICAL ENGINEERING.
650 1 4 _aLIFE SCIENCES.
650 2 4 _aCELL BIOLOGY.
650 2 4 _aBIOPHYSICS/BIOMEDICAL PHYSICS.
650 2 4 _aNEUROSCIENCES.
650 2 4 _aHUMAN PHYSIOLOGY.
650 2 4 _aPHARMACOLOGY/TOXICOLOGY.
650 2 4 _aCARDIOLOGY.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780306478406
830 0 _aMolecular Biology Intelligence Unit
856 4 0 _uhttp://dx.doi.org/10.1007/0-387-27526-6
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c56680
_d56680