000			03527nam a22005415i 4500
001			978-0-387-32442-5
003			DE-He213
005			20250710083949.0
007			cr nn 008mamaa
008			100301s2006 xxu| s |||| 0|eng d
020			_a9780387324425 _a99780387324425
024	7		_a10.1007/0-387-32442-9 _2doi
082	0	4	_a611 _223
100	1		_aHollyfield, Joe G. _eeditor.
245	1	0	_aRetinal Degenerative Diseases _h[recurso electrónico] / _cedited by Joe G. Hollyfield, Robert E. Anderson, Matthew M. LaVail.
264		1	_aBoston, MA : _bSpringer US, _c2006.
300			_aXXII, 562 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v572
505	0		_aFrom the contents Genetic Factors Modifying Clinical Expression of Autosomal Dominant Rp -- Disease-Associated Variants of The Rod-Derived Cone Viability Factor (Rdcvf) In Leber Congenital Amaurosis. Rod-Derived Cone Viability Variants in Lca -- Leber Congenital Amaurosis: Survey of The Genetic Heterogeneity, Refinement of The Clinical Definition and Phenotype-Genotype Correlations as A Strategy For Molecular Diagnosis. Clinical and Molecular Survey in Lca -- A First Locus For Isolated Autosomal Recessive Optic Atrophy (Roa1) Maps To Chromosome 8q21-Q22 -- Rcc1-Like Domain and ORF15: Essentials in Rpgr Gene -- Choroidal Neovascularization in Patients with Adult-Onset Foveomacular Dystrophy Caused by Mutations in the Rds/Peripherin Gene -- Biochemical Characterisation of the C1QTNF5 Gene Associated With Late-Onset Retinal Degeneration. A Genetic Model of Age-Related Macular Degeneration -- Bietti Crystalline Corneoretinal Dystrophy Associated with Cyp4v2 Gene Mutations -- Fundus Appearance Of Choroideremia Using Optical Coherence Tomograpy -- A2e, A Fluorophore Of Rpe Lipofuscin, Can Destabilie Membrane -- Amino-Retinoid Compounds in The Human Retinal Pigment Epithelium -- Annexins In Bruch's Membrane and Drusen -- Molecular Mechanisms of Photoreceptor Degeneration in RP Caused by Impdh1 Mutations.
520			_aRetinal Degenerations is the result of the International Symposium on Retinal degeneration which has become perhaps the most important research meeting in the field. THe topics in this volume explore the etiology, cellular mechanisms, epidemiology, genetics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration.
650		0	_aMEDICINE.
650		0	_aHUMAN ANATOMY.
650		0	_aOPHTHALMOLOGY.
650		0	_aEPIDEMIOLOGY.
650		0	_aQUALITY OF LIFE.
650		0	_aLIFE SCIENCES.
650		0	_aQUALITY OF LIFE _xRESEARCH.
650	1	4	_aMEDICINE & PUBLIC HEALTH.
650	2	4	_aANATOMY.
650	2	4	_aOPHTHALMOLOGY.
650	2	4	_aQUALITY OF LIFE RESEARCH.
650	2	4	_aEPIDEMIOLOGY.
650	2	4	_aLIFE SCIENCES, GENERAL.
700	1		_aAnderson, Robert E. _eeditor.
700	1		_aLaVail, Matthew M. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387284644
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v572
856	4	0	_uhttp://dx.doi.org/10.1007/0-387-32442-9 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SME
942			_2ddc _cER
999			_c57180 _d57180