000			03294nam a22004935i 4500
001			978-0-387-36523-7
003			DE-He213
005			20250710083956.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9780387365237 _a99780387365237
024	7		_a10.1007/978-0-387-36523-7 _2doi
082	0	4	_a616.079 _223
100	1		_aGarcea, Robert L. _eeditor.
245	1	4	_aThe Papillomaviruses _h[recurso electrónico] / _cedited by Robert L. Garcea, Daniel DiMaio.
264		1	_aBoston, MA : _bSpringer US : _bImprint: Springer, _c2007.
300			_aXIX, 419 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPrinciples of Human Tumor Virology -- History of Papillomavirus Research -- Phylogeny and Typing of Papillomaviruses -- The Differentiation-Dependent Life Cycle of Human Papillomaviruses in Keratinocytes -- Papillomavirus Structure and Assembly -- Viral Entry and Receptors -- Human Papillomavirus Transcription -- DNA Replication of Papillomaviruses -- Papillomavirus E5 Proteins -- Human Papillomavirus E6 and E7 Oncogenes -- In Vivo Models for the Study of Animal and Human Papillomaviruses -- The Humoral Immune Response to Human Papillomavirus -- Cell-Mediated Immune Responses to Human Papillomavirus -- Papillomavirus Vaccines -- Clinical Assessment, Therapies, New Tests, and Algorithms -- Possible Worldwide Impact of Prevention of Human Papillomavirus Infection.
520			_aThe papillomaviruses have emerged as the best understood viruses that cause cancer in humans. This volume reviews the remarkable confluence of science, medicine, and public health that recently culminated in the approval of vaccines that prevent many human papillomavirus infections, the first vaccines specifically designed to prevent human cancer. Basic laboratory studies of viral DNA replication, gene expression, protein function, and virus-host interactions have provided fundamental insights into these important processes. Most importantly, human papillomavirus infection has been shown to be a crucial event in the development of several human cancers, most notably cervical cancer, a leading cause of cancer death in women. The Papillomaviruses is an ideal book for scientists, professionals, clinicians, and graduate students in the fields of immunology, infectious disease, virology, microbiology, cell biology, and cancer biology and research.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aIMMUNOLOGY.
650		0	_aMEDICAL VIROLOGY.
650		0	_aEMERGING INFECTIOUS DISEASES.
650		0	_aMICROBIOLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aIMMUNOLOGY.
650	2	4	_aINFECTIOUS DISEASES.
650	2	4	_aVIROLOGY.
650	2	4	_aMICROBIOLOGY.
650	2	4	_aCANCER RESEARCH.
700	1		_aDiMaio, Daniel. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387365220
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-36523-7 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c57504 _d57504