000			03421nam a22004695i 4500
001			978-0-387-39961-4
003			DE-He213
005			20250710083959.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9780387399614 _a99780387399614
024	7		_a10.1007/978-0-387-39961-4 _2doi
082	0	4	_a571.6 _223
100	1		_aRegazzi, Romano. _eauthor.
245	1	0	_aMolecular Mechanisms of Exocytosis _h[recurso electrónico] / _cby Romano Regazzi.
246	3		_aJointly published with Landes Bioscience, Austin, TX, USA
264		1	_aNew York, NY : _bSpringer New York, _c2007.
300			_aIX, 178 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMolecular Biology Intelligence Unit
505	0		_aExocytosis -- Regulation of SNARE Complex Assembly by Second Messengers -- Rab GTPases and Their Role in the Control of Exocytosis -- The Role of Synaptotagmin and Synaptotagmin-Like Protein (Slp) in Regulated Exocytosis -- The Synapsins and the Control of Neuroexocytosis -- Phospholipase D -- Lipid Rafts as Regulators of SNARE Activity and Exocytosis -- Mast Cells as a Model of Nonneuroendocrine Exocytosis -- Acrosomal Exocytosis -- Nonsecretory, Regulated Exocytosis -- Adaptation of the Secretory Machinery to Pathophysiological Conditions.
520			_aExocytosis is a fundamental cellular process that is used by eukaryotic cells to release a variety of biological compounds including peptide hormones and neurotransmitters or to insert specific lipids and proteins in the plasma membrane. In recent years, a multidisciplinary approach promoted an extraordinary progress in the understanding of the molecular mechanisms regulating exocytosis. This led to the discovery of a large number of components belonging to the machinery that governs the fusion of secretory vesicles with plasma membranes in different cell systems, including neuronal and endocrine cells. The basic machinery required for vesicle fusion turned out to be well conserved through evolution from yeast to man. So far, because of the large number of components involved, understanding of the molecular basis of exocytosis has remained the privilege of a relatively small group of specialists. This book, written by recognized experts in the field aims at clarifying for a non-specialist audience the role of the key players in the exocytotic process not only in neuronal and endocrine cells but also in a variety of other relevant cell systems. The book represents a unique collection of up-to-date reviews that will introduce researchers and students to the forefront of this rapidly moving and fascinating field.
650		0	_aLIFE SCIENCES.
650		0	_aNEUROSCIENCES.
650		0	_aCYTOLOGY.
650		0	_aNEUROBIOLOGY.
650	1	4	_aLIFE SCIENCES.
650	2	4	_aCELL BIOLOGY.
650	2	4	_aNEUROBIOLOGY.
650	2	4	_aNEUROSCIENCES.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387399607
830		0	_aMolecular Biology Intelligence Unit
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-39961-4 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c57641 _d57641