000			03929nam a22004215i 4500
001			978-0-387-68639-4
003			DE-He213
005			20250710084007.0
007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9780387686394 _a99780387686394
024	7		_a10.1007/978-0-387-68639-4 _2doi
082	0	4	_a519.5 _223
100	1		_aO'Quigley, John. _eauthor.
245	1	0	_aProportional Hazards Regression _h[recurso electrónico] / _cby John O'Quigley.
264		1	_aNew York, NY : _bSpringer New York, _c2008.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aStatistics for Biology and Health, _x1431-8776
505	0		_aBackground: Probability -- Background: General inference -- Background: Survival analysis -- Marginal survival -- Regression models and subject heterogeneity -- Inference: Estimating equations -- Inference: Functions of Brownian motion -- Inference: Likelihood -- Inference: Stochastic integrals -- Inference: Small samples -- Inference: Changepoint models -- Explained variation -- Explained randomness -- Survival given covariates -- Proofs of theorems, lemmas and corollaries.
520			_aThe place in survival analysis now occupied by proportional hazards models and their generalizations is so large that it is no longer conceivable to offer a course on the subject without devoting at least half of the content to this topic alone. This book focuses on the theory and applications of a very broad class of models-proportional hazards and non-proportional hazards models, the former being viewed as a special case of the latter-which underlie modern survival analysis. Unlike other books in this area the emphasis is not on measure theoretic arguments for stochastic integrals and martingales. Instead, while inference based on counting processes and the theory of martingales is covered, much greater weight is placed on more traditional results such as the functional central limit theorem. This change in emphasis allows us in the book to devote much greater consideration to practical issues in modeling. The implications of different models, their practical interpretation, the predictive ability of any model, model construction, and model selection as well as the whole area of mis-specified models receive a great deal of attention. The book is aimed at both those interested in theory and those interested in applications. Many examples and illustrations are provided. The required mathematical and statistical background for those relatively new to the field is carefully outlined so that the material is accessible to a broad range of levels. John O'Quigley-Director of Research at the French Institut National de la Santé et de la Recherche Médicale and Professor of Mathematics at the University of California at San Diego-has published extensively on the subject of survival analysis, both in theoretical and applied journals. He has taught and carried out collaborative research at several of the world's leading departments of mathematics and statistics including the University of Washington, the Fred Hutchinson Cancer Research Center in Seattle, Harvard University, and Lancaster University, UK.
650		0	_aSTATISTICS.
650		0	_aECONOMETRICS.
650	1	4	_aSTATISTICS.
650	2	4	_aSTATISTICS FOR LIFE SCIENCES, MEDICINE, HEALTH SCIENCES.
650	2	4	_aECONOMETRICS.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387251486
830		0	_aStatistics for Biology and Health, _x1431-8776
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-68639-4 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SMA
942			_2ddc _cER
999			_c58005 _d58005