000			03847nam a22005415i 4500
001			978-0-387-68919-7
003			DE-He213
005			20250710084008.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9780387689197 _a99780387689197
024	7		_a10.1007/0-387-68919-2 _2doi
082	0	4	_a571.4 _223
100	1		_aChung, Shin-Ho. _eeditor.
245	1	0	_aBiological Membrane Ion Channels _h[recurso electrónico] : _bDynamics, Structure, and Applications / _cedited by Shin-Ho Chung, Olaf S. Andersen, Vikram Krishnamurthy.
264		1	_aNew York, NY : _bSpringer New York, _c2007.
300			_aXIV, 658p. 168 illus. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aBiological And Medical Physics Biomedical Engineering, _x1618-7210
505	0		_aIon Channels, from Fantasy to Fact in Fifty Years1 -- Specific Channel Types -- Gramicidin Channels: Versatile Tools -- Voltage-Gated Ion Channels -- Voltage-Gated Potassium Channels -- BKCa-Channel Structure and Function -- Voltage-Gated Sodium Channels -- Calcium Channels -- Chloride Transporting CLC Proteins1 -- Ligand-Gated Ion Channels: Permeation and Activation1 -- Mechanosensitive Channels -- TRP Channels -- Ion Channels in Epithelial Cells -- Theoretical Approaches -- Poisson-Nernst-Planck Theory of Ion Permeation Through Biological Channels -- A Mesoscopic-Microscopic Perspective on Ion Channel Permeation Energetics: The Semi-Microscopic Approach1 -- Brownian Dynamics: Simulation for Ion Channel Permeation1 -- Molecular Dynamics Simulation Approaches to K Channels -- Emerging Technologies -- Patch-Clamp Technologies for Ion Channel Research -- Gated Ion Channel-Based Biosensor Device -- Signal Processing Based on Hidden Markov Models for Extracting Small Channel Currents.
520			_aIon channels are biological nanotubes that are formed by membrane proteins. Because ion channels regulate all electrical activities in living cells, understanding their mechanisms at a molecular level is a fundamental problem in biology. This book deals with recent breakthroughs in ion-channel research that have been brought about by the combined effort of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these exquisitely designed biomolecules. With chapters by leading experts, the book is aimed at researchers in nanodevices and biosensors, as well as advanced undergraduate and graduate students in biology and the physical sciences. Key Features Presents the latest information on the molecular mechanisms of ion permeation through membrane ion channels Uses schematic diagrams to illustrate important concepts in biophysics Written by leading researchers in the area of ion channel investigations
650		0	_aPHYSICS.
650		0	_aNEUROSCIENCES.
650		0	_aBIOTECHNOLOGY.
650		0	_aBIOCHEMISTRY.
650		0	_aNEUROBIOLOGY.
650		0	_aBIOMEDICAL ENGINEERING.
650	1	4	_aPHYSICS.
650	2	4	_aBIOPHYSICS/BIOMEDICAL PHYSICS.
650	2	4	_aNEUROSCIENCES.
650	2	4	_aBIOMEDICAL ENGINEERING.
650	2	4	_aNEUROBIOLOGY.
650	2	4	_aBIOTECHNOLOGY.
650	2	4	_aANIMAL BIOCHEMISTRY.
700	1		_aAndersen, Olaf S. _eeditor.
700	1		_aKrishnamurthy, Vikram. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387333236
830		0	_aBiological And Medical Physics Biomedical Engineering, _x1618-7210
856	4	0	_uhttp://dx.doi.org/10.1007/0-387-68919-2 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-PHA
942			_2ddc _cER
999			_c58053 _d58053