000			04111nam a22004935i 4500
001			978-0-387-68945-6
003			DE-He213
005			20250710084008.0
007			cr nn 008mamaa
008			100301s2009 xxu| s |||| 0|eng d
020			_a9780387689456 _a99780387689456
024	7		_a10.1007/978-0-387-68945-6 _2doi
082	0	4	_a614.5999 _223
100	1		_aPipas, James. _eeditor.
245	1	0	_aDNA Tumor Viruses _h[recurso electrónico] / _cedited by James Pipas, Blossom Damania.
264		1	_aNew York, NY : _bSpringer US, _c2009.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aPolyomavirus Life Cycle -- Transformation by Polyomaviruses -- Polyomaviruses and Disease -- The Life Cycle of Human Papillomaviruses -- Papillomavirus Transformation -- Papillomaviruses: Biology, Diversity, and Pathogenesis -- Adenovirus Transformation -- Overview of the Large DNA Tumor Viruses -- Epidemiology of EBV Infection -- EBV Diseases -- The Epstein-Barr Virus Genome -- Epstein-Barr Virus Transforming Proteins: Biologic Properties and Contribution to Oncogenesis -- The Epstein-Barr Virus Lytic Life Cycle -- Epstein-Barr Virus Latent Infection Nuclear Proteins: Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival -- Epstein-Barr Virus Entry -- EBV Immunotherapy -- KSHV Epidemiology and Subtype Evolution -- to Diseases Associated with Kaposi's Sarcoma-Associated Herpesvirus -- Organization and Expression of the Kaposi's Sarcoma-Associated Herpesvirus Genome -- KSHV Latent Genes and Their Regulation -- Regulation of Expression, Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation -- HHV-8/KSHV Proteins Involved in Signaling and Transformation -- KSHV Entry and Infection of Target Cells -- KSHV Immune Evasion -- Non-coding Regulatory RNAs of the DNA Tumor Viruses -- AIDS and Associated Malignancies -- Primate Models for Gammaherpesvirus-Associated Malignancies -- Murine Gammaherpesvirus 68 Infection of Mice: A Small Animal Model for Characterizing Basic Aspects of Gammaherpesvirus Pathogenesis.
520			_aThe DNA tumor viruses are central to many branches of molecular and cellular biology. This very diverse group of viruses attack common cellular pathways, which makes them powerful tools for understanding how multiple complex pathways are integrated. Additionally, the unique mechanisms employed by each viral system to alter cellular functions serve as powerful molecular probes for the identification of new targets and pathways. The scientific impact of the DNA tumor viruses extends far beyond their etiologic role in human cancers, or their contributions to our basic understanding of the cellular pathways that drive tumorigenesis. Currently, research on these viruses lies at the interface of cancer and the innate and adaptive immune response, investigating how infectious agents influence, evade, and utilize systems that regulate these processes. Thus, DNA tumor viruses serve as models for the systems biology of host-pathogen interactions. "DNA Tumor Viruses," edited by Blossom Damania and James M. Pipas, summarizes recent advances in our understanding of this diverse and fascinating collection of viruses.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aHUMAN GENETICS.
650		0	_aMICROBIOLOGY.
650		0	_aMEDICAL VIROLOGY.
650		0	_aCYTOLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aHUMAN GENETICS.
650	2	4	_aVIROLOGY.
650	2	4	_aMEDICAL MICROBIOLOGY.
650	2	4	_aCELL BIOLOGY.
700	1		_aDamania, Blossom. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387689449
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-68945-6 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c58057 _d58057