000			03354nam a22004575i 4500
001			978-0-387-70956-7
003			DE-He213
005			20250710084011.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9780387709567 _a99780387709567
024	7		_a10.1007/978-0-387-70956-7 _2doi
082	0	4	_a612.8 _223
100	1		_aPasterkamp, R. J. _eeditor.
245	1	0	_aSemaphorins: Receptor and Intracellular Signaling Mechanisms _h[recurso electrónico] / _cedited by R. J. Pasterkamp.
264		1	_aNew York, NY : _bSpringer New York, _c2007.
300			_aXIV, 147 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v600
505	0		_aThe CRMP Family of Proteins and Their Role in Sema3A Signaling -- GTPases in Semaphorin Signaling -- Intracellular Kinases in Semaphorin Signaling -- MICAL Flavoprotein Monooxygenases: Structure, Function and Role in Semaphorin Signaling -- Signaling of Secreted Semaphorins in Growth Cone Steering -- Modulation of Semaphorin Signaling by Ig Superfamily Cell Adhesion Molecules -- Proteoglycans as Modulators of Axon Guidance Cue Function -- Semaphorin Signals in Cell Adhesion and Cell Migration: Functional Role and Molecular Mechanisms -- Semaphorin Signaling During Cardiac Development -- Semaphorin Signaling in Vascular and Tumor Biology -- Semaphorin Signaling in the Immune System.
520			_aThe book summarizes our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins. Originally these protein were identified as "axon guidance cues" important for the formation of nerve tracts but now it is realized that semaphorins subserve several distinct functions in a multitude of organ systems. The purpose of this book is to summarize our knowledge and make it available as a useful and comprehensive tool for the scientific community. This book will both be interesting for people working in the field as well as colleagues that work in other fields of science and would like to learn more about semaphorins and associated signaling mechanisms. All the latest techniques and results are summarized in this book which covers the entire semaphorin field from neurosciences to cardiovascular research and beyond. The strength of this book is that it gives a very comprehensive overview of all our knowledge of semaphorin biology and signaling and allows one to compare semaphorin functions between different biological systems.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aIMMUNOLOGY.
650		0	_aNEUROSCIENCES.
650	1	4	_aBIOMEDICINE.
650	2	4	_aNEUROSCIENCES.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aIMMUNOLOGY.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387709550
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v600
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-70956-7 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c58186 _d58186