000			03117nam a22004695i 4500
001			978-0-387-71749-4
003			DE-He213
005			20250710084013.0
007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9780387717494 _a99780387717494
024	7		_a10.1007/978-0-387-71749-4 _2doi
082	0	4	_a572.6 _223
100	1		_aRemedios, Cristobal G. _eeditor.
245	1	0	_aActin-Binding Proteins and Disease _h[recurso electrónico] / _cedited by Cristobal G. Remedios, Deepak Chhabra.
264		1	_aNew York, NY : _bSpringer New York, _c2008.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aProtein Reviews ; _v8
505	0		_aActin -- Actin: An Overview of Its Structure and Function -- Actin Genetic Diseases -- Actin-Binding Drugs: An Elegant Tool to Dissect Subcellular Processes in Endothelial and Cancer Cells -- Autoantigenicity of Actin -- Actin-Binding Proteins -- Overview: Actin-Binding Protein Function and Its Relation to Disease Pathology -- ADF/Cofilin, Actin Dynamics, and Disease -- Gelsolin and Disease -- Profilin -- The Roles of Thymosin ?4 in Cell Migration and Cell-to-Cell Signaling in Disease -- Actin-Binding Proteins -- Actin and Actin-Binding Proteins in Cancer Progression and Metastasis -- Diseases with Abnormal Actin and Actin-Binding Proteins in Leukocyte and Nonmuscle Cells -- The Role of PIP2 in Actin, Actin-Binding Proteins and Disease -- Intracellular Pathogens and the Actin Cytoskeleton -- Actin and Its Binding Proteins in Heart Failure.
520			_aThis volume, written by experts in the field, is the first to deal with the relationship between human disease and the actin cytoskeleton. It provides overviews of actin and selected actin-binding proteins, and then focuses on diseases that involve these proteins. Specific chapters deal with actin, cofilin, profilin, gelsolin and thymosin ¾4. Other chapters discuss the roles of multiple actin-binding proteins in cancer and metastasis, leukocyte disorders, and heart failure, and there is a chapter that describes how intracellular pathogens use the host actin cytoskeleton. This seminal volume is intended for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
650		0	_aLIFE SCIENCES.
650		0	_aBIOCHEMISTRY.
650		0	_aPROTEOMICS.
650		0	_aCYTOLOGY.
650	1	4	_aLIFE SCIENCES.
650	2	4	_aPROTEOMICS.
650	2	4	_aCELL BIOLOGY.
650	2	4	_aBIOCHEMISTRY, GENERAL.
700	1		_aChhabra, Deepak. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387717470
830		0	_aProtein Reviews ; _v8
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-71749-4 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c58282 _d58282