000			03640nam a22004575i 4500
001			978-0-387-75532-8
003			DE-He213
005			20250710084022.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9780387755328 _a99780387755328
024	7		_a10.1007/978-0-387-75532-8 _2doi
082	0	4	_a571.6 _223
100	1		_aLeón, Rosa. _eeditor.
245	1	0	_aTransgenic Microalgae as Green Cell Factories _h[recurso electrónico] / _cedited by Rosa León, Aurora Galván, Emilio Fernández.
264		1	_aNew York, NY : _bSpringer New York, _c2007.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v616
505	0		_aNuclear Transformation of Eukaryotic Microalgae -- Transformation of Cyanobacteria -- Molecular Biology and the Biotechnological Potential of Diatoms -- Tools and Techniques for Chloroplast Transformation of Chlamydomonas -- Influence of Codon Bias on the Expression of Foreign Genes in Microalgae -- In the Grip of Algal Genomics -- Insertional Mutagenesis as a Tool to Study Genes/Functions in Chlamydomonas -- Optimization of Recombinant Protein Expression in the Chloroplasts of Green Algae -- Phycoremediation of Heavy Metals Using Transgenic Microalgae -- Hydrogen Fuel Production by Transgenic Microalgae -- Microalgal Vaccines.
520			_aMicroalgae have been largely cultured and commercialized as food and feed additives, and their potential as source of high-added value compounds is well known. But, in contrast to the large number of genetically modified bacteria, yeast and even higher plants, only a few species of microalgae have been genetically transformed with efficiency. Initial difficulties in the expression of foreign genes in microalgae have been progressively overcome, and powerful molecular tools for their genetic engineering are now on hand. A considerable collection of promoters and selectable marker genes and an increasing number of genomic or cDNA sequences have become available in recent years. More work is needed to transform new species of microalgae, specially those that have commercial value, so that it would be possible to increase the productivity of traditional compounds or synthesize novel ones. Silencing transgenes remains as an important limitation for stable expression of foreign genes. This problem is not unique to microalgae since it has also been observed in plants, animals and fungi. A better understanding of the mechanisms that control the regulation of gene expression in eukaryotes is therefore needed. In this book a group of outstanding researchers working on different areas of microalgae biotechnology offer a global vision of the genetic manipulation of microalgae and their applications.
650		0	_aLIFE SCIENCES.
650		0	_aCYTOLOGY.
650		0	_aMICROBIAL ECOLOGY.
650	1	4	_aLIFE SCIENCES.
650	2	4	_aCELL BIOLOGY.
650	2	4	_aMICROBIAL ECOLOGY.
700	1		_aGalván, Aurora. _eeditor.
700	1		_aFernández, Emilio. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387755311
830		0	_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v616
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-75532-8 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c58698 _d58698