000			03987nam a22004935i 4500
001			978-0-387-78608-7
003			DE-He213
005			20251006084419.0
007			cr nn 008mamaa
008			110402s2009 xxu| s |||| 0|eng d
020			_a9780387786087
020			_a99780387786087
024	7		_a10.1007/978-0-387-78608-7 _2doi
100	1		_aWebster, Thomas J. _eeditor.
245	1	0	_aSafety of Nanoparticles _h[electronic resource] : _bFrom Manufacturing to Medical Applications / _cedited by Thomas J. Webster.
264		1	_aNew York, NY : _bSpringer New York, _c2009.
300			_aXII, 239p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aNanostructure Science and Technology, _x1571-5744
505	0		_aDeveloping Practices for Safe Handling of Nanoparticles and Nanomaterials in a Development-Stage Enterprise: A Practical Guide for Research and Development Organizations -- Cytotoxicity of Photoactive Nanoparticles -- Breeching Epithelial Barriers - Physiochemical Factors Impacting Nanomaterial Translocation and Toxicity -- Safety and Efficacy of Nano/Micro Materials -- Biomedical Applications of Nanoparticles -- Unexpected Reactions by In Vivo Applications of PEGylated Liposomes -- Hydrogel Nanocomposites: Biomedical Applications, Biocompatibility, and Toxicity Analysis -- Cytotoxicity and Genotoxicity of Carbon Nanomaterials -- Calcium Phosphate Nanoparticles: Toxicology and Lymph Node Targeting for Cancer Metastasis Prevention -- Nanoparticles for Cancer Diagnosis and Therapy.
520			_a"Environmental safety and health has become an existential issue for the nanotechnology movement, and the international community is responding to this challenge with major multi-disciplinary research efforts. This compilation covers both the toxicology and biomedical applications of nanomaterials in a form that will be a useful reference and starting point for people working in or entering this rapidly growing field." --Dr. Robert Hurt, Director, The Institute for Molecular and Nanoscale Innovation (IMaNI) at Brown University, Professor, Brown University, Providence, RI 02917 USA In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first detailed overviews of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.
650		0	_aMATERIALS.
650		0	_aIMMUNOLOGY.
650		0	_aBIOMEDICAL ENGINEERING.
650		0	_aNANOTECHNOLOGY.
650		0	_aSURFACES (PHYSICS).
650	1	4	_aMATERIAL SCIENCE.
650	2	4	_aNANOTECHNOLOGY.
650	2	4	_aBIOMEDICAL ENGINEERING.
650	2	4	_aCHARACTERIZATION AND EVALUATION OF MATERIALS.
650	2	4	_aBIOPHYSICS/BIOMEDICAL PHYSICS.
650	2	4	_aIMMUNOLOGY.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387786070
830		0	_aNanostructure Science and Technology, _x1571-5744
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-78608-7 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-CMS
942			_2ddc _cER
999			_c59091 _d59091