000 02387nam a22004215i 4500
001 978-0-387-78632-2
003 DE-He213
005 20251006084419.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387786322
020 _a99780387786322
024 7 _a10.1007/978-0-387-78632-2
_2doi
082 0 4 _a572
_223
100 1 _aRuhrberg, Christiana.
_eauthor.
245 1 0 _aVEGF in Development
_h[electronic resource] /
_cby Christiana Ruhrberg.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMolecular Biology Intelligence Unit
505 0 _aThe Biology of Vascular Endothelial Cell Growth Factor Isoforms -- VEGF Receptor Signalling in Vertebrate Development -- VEGF Gene Regulation -- Embryonic Vasculogenesis and Hematopoietic Specification -- Role of VEGF in Organogenesis -- VEGF and Endothelial Guidance in Angiogenic Sprouting -- Vascular and Nonvascular Roles of VEGF in Bone Development -- VEGF in the Nervous System.
520 _aThis book is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit. In addition, VEGFA is emerging as a versatile patterning factor for several non-endothelial cell types in vertebrates. Thus, it plays a central role during organ development at multiple levels, including blood vessel growth, vessel-mediated organ induction and tissue differentiation.
650 0 _aLIFE SCIENCES.
650 0 _aBIOCHEMISTRY.
650 1 4 _aLIFE SCIENCES.
650 2 4 _aBIOCHEMISTRY, GENERAL.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387786315
830 0 _aMolecular Biology Intelligence Unit
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-78632-2
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c59092
_d59092