000 03164nam a22004095i 4500
001 978-0-387-78885-2
003 DE-He213
005 20251006084420.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387788852
020 _a99780387788852
024 7 _a10.1007/978-0-387-78885-2
_2doi
082 0 4 _a610
_223
100 1 _aUtsumi, Ryutaro.
_eeditor.
245 1 0 _aBacterial Signal Transduction: Networks and Drug Targets
_h[electronic resource] /
_cedited by Ryutaro Utsumi.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v631
505 0 _ato Bacterial Signal Transduction Networks -- The PhoQ/PhoP Regulatory Network of Salmonella enterica -- Structural Basis of the Signal Transduction in the Two-Component System -- The Two-Component Network and the General Stress Sigma Factor RpoS (?S) in Escherichia coli -- Small RNAs Controlled by Two-Component Systems -- Two-Component Signaling and Gram Negative Envelope Stress Response Systems -- Dual Regulation with Ser/Thr Kinase Cascade and a His/Asp TCS in Myxococcus xanthus -- Two-Component Signaling Systems and Cell Cycle Control in Caulobacter crescentus -- RegB/RegA, A Global Redox-Responding Two-Component System -- The BvgS/BvgA Phosphorelay System of Pathogenic Bordetellae -- Capturing the VirA/VirG TCS of Agrobacterium tumefaciens -- Quorum Sensing and Biofilm Formation by Streptococcus mutans -- The Roles of Two-Component Systems in Virulence of Pathogenic Escherichia coli and Shigella spp. -- Vancomycin Resistance VanS/VanR Two-Component Systems -- Tearing Down the Wall: Peptidoglycan Metabolism and the WalK/WalR (YycG/YycF) Essential Two-Component System -- Inhibitors Targeting Two-Component Signal Transduction.
520 _aThis fascinating book encourages many microbiologists and students to enter the new world of signal transduction in microbiology. Over the past decade, a vast amount of exciting new information on the signal transduction pathway in bacteria has been brought to light. Reports on these developments have been put together in this book, Bacterial Signal Transduction: Networks and Drug Targets. The aim of this book is to provide an incentive for graduate students, academic scientists, and researchers in the pharmaceutical industry to further elucidate the TCS networks and apply them in the search for novel drugs.
650 0 _aMEDICINE.
650 1 4 _aBIOMEDICINE.
650 2 4 _aBIOMEDICINE GENERAL.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387788845
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v631
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-78885-2
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c59119
_d59119