000			02934nam a22004335i 4500
001			978-0-387-89611-3
003			DE-He213
005			20251006084430.0
007			cr nn 008mamaa
008			110414s2009 xxu| s |||| 0|eng d
020			_a9780387896113
020			_a99780387896113
024	7		_a10.1007/978-0-387-89611-3 _2doi
082	0	4	_a614.5999 _223
100	1		_aMajumder, Sadhan. _eeditor.
245	1	0	_aStem Cells and Cancer _h[electronic resource] / _cedited by Sadhan Majumder.
264		1	_aNew York, NY : _bSpringer New York, _c2009.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aStem Cells and Cancer: An Introduction -- Molecular Regulation of the State of Embryonic Stem Cells -- MicroRNAs in Stem Cells and Cancer Stem Cells -- Cancer Stem Cells and Metastasis: Emerging Themes and Therapeutic Implications -- Stem Cells in Leukemia and Other Hematological Malignancies -- Prostate Cancer Stem Cells -- Breast Cancer Stem Cells -- Stem Cells and Lung Cancer -- Cancer Stem Cells in Colorectal Cancer -- Cancer Stem Cells and Skin Cancer -- Lineage Relationships Connecting Germinal Regions to Brain Tumors.
520			_aCancer is a major cause of human morbidity and mortality worldwide. Despite decades of basic and clinical research, the outcome for many cancer patients is still dismal. Although the existence of "stem-like" cells in cancer was hypothesized more than 150 years ago, recent discoveries have the potential to revolutionize cancer therapy. In particular, we now know that many cancers contain a fraction of self-renewing, drug- and radiation-resistant cells (cancer stem cells or cancer-initiating cells) and it is these cells-and not the major bulk of the tissue-that are the root cause for cancer initiation, relapse and metastasis. In a single volume, Stem Cells and Cancer offers up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies across all major types of cancer. It provides timely, cutting-edge information about cancer stem cells from the perspectives of both the basic and clinical sciences.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aCYTOLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aONCOLOGY.
650	2	4	_aCELL BIOLOGY.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387896106
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-89611-3 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c59467 _d59467