000 03217nam a22004095i 4500
001 978-1-4020-3206-6
003 DE-He213
005 20251006084452.0
007 cr nn 008mamaa
008 120123s2006 ne | s |||| 0|eng d
020 _a9781402032066
020 _a99781402032066
024 7 _a10.1007/978-1-4020-3206-6
_2doi
082 0 4 _a579
_223
100 1 _aKoch, Arthur L.
_eauthor.
245 1 4 _aThe Bacteria: Their Origin, Structure, Function and Antibiosis
_h[electronic resource] /
_cby Arthur L. Koch.
250 _a1.
264 1 _aDordrecht :
_bSpringer Netherlands,
_c2006.
300 _aX, 224 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aOrigin of Bacteria -- The Origin of Life Based on Physical Principles -- Preamble to Life -- The First Cell -- Development of Cell Physiology and Diversity -- Wall Structure -- Covalent Bonds and Tensile Strength of Materials -- Structure of the Fabric that Covers a Bacterium -- The Covalently Linked Sacculus: the Nona-Muropeptide Model -- The Structure of the Tessera; the Unit Structure of Murein Wall -- Extrusion and Incorporation into Wall -- The Role of Poles in the Growth Strategy of Bacteria -- Bacterial Morphologies -- Sidewalls of Gram-Negative Rod-Shaped Bacteria -- Growth Strategies for Gram-Positive Cells -- Wall Growth Strategies for Gram-Negative Cells -- Commas, Vibrios, Spirilla, and Helicobacters; Tapered and Branched Bacteria -- Spirochetes and Spiroplasma and the Special Strategies for CWD (Cell Wall Deficient) Cells -- Coccal Versus Rod-Shaped Cells, and the First Bacterium -- Diseases: Old and New -- Antibiosis -- Lysozymes as Alternatives to ?-lactams Antibiotics Acting on the Bacterial Wall -- Development of Wall Antibiotics and Bacterial Counter-Measures -- Antibiotics and Resistance, with an Emphasis on Aminoglycosides -- Future Chemotherapy Aimed at the Bacterial Murein.
520 _aThe book's purpose is to explain from the development of life on earth to the evolution of diversity. It is this diversity that led, almost automatically to the development of pathogens and predators. The relationship of pathogens and host lead to the development of antibiotics and resistance mechanism. Man has extended this process and we now have a situation in which new antibiotics only are effective for a short time. If we are to create long term antibiotics we must design them with this history in mind. Understanding antibiotic chemotherapy at the ecological level is necessary for more permanent advances in development and in the usage of antibiotic agents both old, new, and in the future.
650 0 _aLIFE SCIENCES.
650 0 _aMICROBIOLOGY.
650 1 4 _aLIFE SCIENCES.
650 2 4 _aMICROBIOLOGY.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781402066252
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4020-3206-6
_zVer el texto completo en las instalaciones del CICY
912 _aZDB-2-SBL
942 _2ddc
_cER
999 _c60375
_d60375