000			03525nam a22004695i 4500
001			978-1-4020-3242-4
003			DE-He213
005			20251006084453.0
007			cr nn 008mamaa
008			100301s2005 ne | s |||| 0|eng d
020			_a9781402032424
020			_a99781402032424
024	7		_a10.1007/1-4020-3242-0 _2doi
082	0	4	_a579 _223
100	1		_aPalese, Peter. _eeditor.
245	1	0	_aModulation of Host Gene Expression and Innate Immunity by Viruses _h[electronic resource] / _cedited by Peter Palese.
264		1	_aDordrecht : _bSpringer Netherlands, _c2005.
300			_aXIII, 304 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aViruses and the Innate Immune System -- How Viruses Elicit Interferon Production -- Genes Modulated by Interferons and Double-Stranded RNA -- Immunoevasive Strategies: Host and Virus -- Interferon Antagonists of Influenza Viruses -- The Anti-Interferon Mechanisms of Paramyxoviruses -- The Strategy of Conquest -- Immunomodulation by Poxviruses -- Interferon Antagonists Encoded by Emerging RNA Viruses -- Viral Pathogenesis and Toll-Like Receptors -- Digesting Oneself and Digesting Microbes -- Genetic Variation in Host Defenses and Viral Infections.
520			_aThis book is an excellent, up-to-date reference on a relatively young area of research in which virology, cellular biology and molecular pathogenesis govern the principles of coinvestigation. Thus, the book will be of great interest to virologists, molecular immunologists and biologists, and biochemists but also to clinical pharmacologists in the long-term search for new antiviral agents. Ulrich Desselberger, Gif-sur-Yvette/Cambridge. Infection of a naïve (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity). The outcome of this interaction is influenced by the genes of the virus as well as the genes of the host. Interestingly, different viruses do it in different ways. Not only is there a plethora of mechanisms used by the invading organisms, but the host has also evolved a great variety of redundant and robust countermeasures. This interplay of host and virus represents one of the most significant frontiers in biology today. A clearer understanding of the mechanisms involved will arm us with better strategies to deal with viruses, including emerging pathogens and potential bioterrorism agents. This book is sure to benefit students, scientists, and physicians working in the areas of virology, immunology, microbiology, and infectious diseases. Pharmaceutical industry professionals will also find interest in this illuminating look into virus/host interactions.
650		0	_aLIFE SCIENCES.
650		0	_aIMMUNOLOGY.
650		0	_aMEDICAL VIROLOGY.
650		0	_aEMERGING INFECTIOUS DISEASES.
650		0	_aMICROBIOLOGY.
650	1	4	_aLIFE SCIENCES.
650	2	4	_aMICROBIOLOGY.
650	2	4	_aIMMUNOLOGY.
650	2	4	_aVIROLOGY.
650	2	4	_aINFECTIOUS DISEASES.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402032417
856	4	0	_uhttp://dx.doi.org/10.1007/1-4020-3242-0 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c60386 _d60386