000			03063nam a22005055i 4500
001			978-1-4020-5129-6
003			DE-He213
005			20251006084518.0
007			cr nn 008mamaa
008			100301s2006 ne | s |||| 0|eng d
020			_a9781402051296
020			_a99781402051296
024	7		_a10.1007/978-1-4020-5129-6 _2doi
082	0	4	_a614.5999 _223
100	1		_aCress, Anne E. _eeditor.
245	1	0	_aCell Adhesion and Cytoskeletal Molecules in Metastasis _h[electronic resource] / _cedited by Anne E. Cress, Raymond B. Nagle.
264		1	_aDordrecht : _bSpringer Netherlands, _c2006.
300			_aXII, 198 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCancer Metastasis - Biology and Treatment, _x1568-2102 ; _v9
505	0		_aCHANGING EXTRACELLULAR MATRIX LIGANDS DURING METASTASIS -- SUPPRESSION AND ALTERATION OF ADHESION STRUCTURES IN HUMAN EPITHELIAL CANCER PROGRESSION -- REGULATION OF CADHERINS DURING PROSTATE CANCER PROGRESSION -- THE ACTIN CYTOSKELETON AND METASTASIS -- CHARACTERIZATION OF THE FERM DOMAIN PROTEIN EHM2 IN HUMAN CANCER CELLS -- CYTOKERATIN 6 EXPRESSION IN PROSTATE STEM CELLS -- EPIGENETIC REGULATION OF GENES THAT AFFECT TUMOR CELL ADHESION -- CELL ADHESION-MEDIATED RADIATION RESISTANCE: THE ROLE OF INTEGRINS AND INTEGRIN PROXIMAL PROTEIN -- CAM-DR: HANGING ON FOR CELL SURVIVAL -- EPITHELIAL CELL SURFACE TARGETING USING SYNTHETIC D-AMINO ACID PEPTIDES.
520			_aIn this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aDERMATOLOGY.
650		0	_aPATHOLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aMOLECULAR MEDICINE.
650	2	4	_aDERMATOLOGY.
650	2	4	_aONCOLOGY.
650	2	4	_aPATHOLOGY.
700	1		_aNagle, Raymond B. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402051289
830		0	_aCancer Metastasis - Biology and Treatment, _x1568-2102 ; _v9
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-5129-6 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c61147 _d61147