000			03388nam a22005055i 4500
001			978-1-4020-5468-6
003			DE-He213
005			20251006084521.0
007			cr nn 008mamaa
008			100301s2007 ne | s |||| 0|eng d
020			_a9781402054686
020			_a99781402054686
024	7		_a10.1007/978-1-4020-5468-6 _2doi
082	0	4	_a570.151 _223
100	1		_aCASSMAN, MARVIN. _eeditor.
245	1	0	_aSystems Biology _h[electronic resource] : _bInternational Research and Development / _cedited by MARVIN CASSMAN, ADAM ARKIN, FRANK DOYLE, FUMIAKI KATAGIRI, DOUGLAS LAUFFENBURGER, CYNTHIA STOKES.
264		1	_aDordrecht : _bSpringer Netherlands, _c2007.
300			_aXVII, 262 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aExecutive Summary and Introduction -- Data and Databases -- Network Inference -- Modeling and Network Organization -- Systems Biology in Plant Research -- Education, National Programs, and Infrastructure in Systems Biology.
520			_aSystems biology is defined for the purpose of this study as the understanding of biological network behaviors, and in particular their dynamic aspects, which requires the utilization of mathematical modeling tightly linked to experiment. This involves a variety of approaches, such as the identification and validation of networks, the creation of appropriate datasets, the development of tools for data acquisition and software development, and the use of modeling and simulation software in close linkage with experiment. All of these are discussed in this volume. Of course, the definition becomes ambiguous at the margins, but at the core is the focus on networks, which makes it clear that the goal is to understand the operation of the systems, rather than the component parts. It was concluded that the U.S. is currently ahead of the rest of the world in systems biology, largely because of earlier investment by funding organizations and research institutions. This is reflected in a large number of active research groups, and educational programs, and a diverse and growing funding base. However, there is evidence of rapid development outside the U.S., much of it begun in the last two to three years. Overall, however, the picture is of an active field in the early stages of explosive growth. This volume is aimed at academic researchers, government research agency representatives and graduate students.
650		0	_aMATHEMATICS.
650		0	_aBIOINFORMATICS.
650		0	_aDEVELOPMENTAL BIOLOGY.
650		0	_aBIOLOGY _xMATHEMATICS.
650	1	4	_aMATHEMATICS.
650	2	4	_aMATHEMATICAL BIOLOGY IN GENERAL.
650	2	4	_aBIOINFORMATICS.
650	2	4	_aDEVELOPMENTAL BIOLOGY.
700	1		_aARKIN, ADAM. _eeditor.
700	1		_aDOYLE, FRANK. _eeditor.
700	1		_aKATAGIRI, FUMIAKI. _eeditor.
700	1		_aLAUFFENBURGER, DOUGLAS. _eeditor.
700	1		_aSTOKES, CYNTHIA. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402054679
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-5468-6 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SMA
942			_2ddc _cER
999			_c61289 _d61289