000			04161nam a22005055i 4500
001			978-1-4020-5900-1
003			DE-He213
005			20251006084527.0
007			cr nn 008mamaa
008			100301s2007 ne | s |||| 0|eng d
020			_a9781402059001
020			_a99781402059001
024	7		_a10.1007/978-1-4020-5900-1 _2doi
082	0	4	_a571.4 _223
100	1		_aPuglisi, Joseph D. _eeditor.
245	1	0	_aStructure and Biophysics - New Technologies for Current Challenges in Biology and Beyond _h[electronic resource] / _cedited by Joseph D. Puglisi.
246	3		_aProceedings of the NATO Advanced Study Institute on Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond, held in Erice, Italy, 22 June - 3 July 2005
264		1	_aDordrecht : _bSpringer Netherlands, _c2007.
300			_aVI, 153 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aNATO Science Series
505	0		_aStructural Genomics by NMR Spectroscopy -- Investigation of Proteins in Living Bacteria with In-Cell NMR Experiments -- Protein-Membrane Interactions: Lessons from In Silico Studies -- Anything Goes - Protein Structural Polymorphism -- Tandem Interactions in the trp Repressor System may Regulate Binding to Operator DNA -- Basic Principles of RNA NMR Spectroscopy -- Probabilistic Structure Calculation -- Molecular Insights into PKR Activation by Viral Double-Stranded RNA -- Structural Dynamic Approach as Rational Input for Drug Design -- Max Perutz: Chemist, Molecular Biologist, and Human Rights Activist -- Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance, and Antibiotics Inactivation.
520			_aThis volume is a collection of articles from the proceedings of the ISSBMR 7th Course: Structure and Biophysics - New Technologies for Current Challenges in Biology and Beyond. This NATO Advanced Institute (ASI) was held in Erice at the Ettore Majorana Foundation and Centre for Scientific Culture on 22 June through 3 July 2005. The ASI brought together a diverse group of experts in the fields of Structural Biology, Biophysics and Physics. Prominent lecturers, from seven different countries, and students from around the world participated in the NATO ASI organized by Professors Joseph Puglisi (Stanford University, USA) and Alexander Arseniev (Moscow, RU). Advances in nuclear magnetic resonance spectroscopy (NMR) and x-ray crystallography have allowed the three-dimensional structures of many biological macromolecules and their complexes, including the ribosome and RNA polymerase to be solved. Fundamental principles of NMR spectroscopy and dynamics, x-ray crystallography, computation and experimental dynamics were taught in the context of important biological applications. The ASI addressed the treatment and detection of bioterrorism agents, and focused on critical partner country priorities in biotechnology, materials and drug discovery. The range of topics represent the diversity of critical problems between structural biology, biochemistry and biophysics, in which lies the fertile ground of drug development, biotechnology and new materials. The individual articles represent the state of the art in each area and provide a guide to the original literature in this rapidly developing field.
650		0	_aPHYSICS.
650		0	_aBIOTECHNOLOGY.
650		0	_aPARTICLES (NUCLEAR PHYSICS).
650		0	_aCRYSTALLOGRAPHY.
650		0	_aBIOMEDICAL ENGINEERING.
650	1	4	_aPHYSICS.
650	2	4	_aBIOPHYSICS/BIOMEDICAL PHYSICS.
650	2	4	_aSOLID STATE PHYSICS AND SPECTROSCOPY.
650	2	4	_aCRYSTALLOGRAPHY.
650	2	4	_aBIOTECHNOLOGY.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402058981
830		0	_aNATO Science Series
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-5900-1 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-PHA
942			_2ddc _cER
999			_c61485 _d61485