000			03774nam a22005295i 4500
001			978-1-4020-6051-9
003			DE-He213
005			20251006084528.0
007			cr nn 008mamaa
008			100301s2007 ne | s |||| 0|eng d
020			_a9781402060519
020			_a99781402060519
024	7		_a10.1007/978-1-4020-6051-9 _2doi
082	0	4	_a616.96 _223
100	1		_aFlohé, Leopold. _eeditor.
245	1	0	_aPeroxiredoxin Systems _h[electronic resource] : _bStructures and Functions / _cedited by Leopold Flohé, J. Robin Harris.
264		1	_aDordrecht : _bSpringer Netherlands, _c2007.
300			_aXIV, 407 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aSubcellular Biochemistry, _x0306-0225 ; _v44
505	0		_aEvolution of the Peroxiredoxins -- Structural Survey of the Peroxiredoxins -- The Catalytic Mechanism of Peroxiredoxins -- Kinetics of Peroxiredoxins and their Role in the Decomposition of Peroxynitrite -- The Peroxiredoxin Repair Proteins -- Peroxiredoxins in Bacterial Antioxidant Defense -- The NADH Oxidase-Prx System in Amphibacillus Xylanus -- Peroxiredoxin Systems in Mycobacteria -- Peroxiredoxin Systems of Protozoal Parasites -- The Trypanothione System -- Functions of Typical 2-Cys Peroxiredoxins in Yeast -- The Dual Function of Plant Peroxiredoxins in Antioxidant Defence and Redox Signaling -- Mitochondrial Peroxiredoxins -- Peroxiredoxins in the Lung with Emphasis on Peroxiredoxin VI -- Peroxiredoxins in Gametogenesis and Embryo Development -- Peroxiredoxins in the Central Nervous System -- Stress-Induced Peroxiredoxins.
520			_aThe peroxiredoxins represent an important emerging family of sulfhydryl-linked antioxidant proteins, apparently ubiquitously present in all known organisms. The antioxidant function of the peroxiredoxins complements that of other enzymic and non-enzymic systems within the cell. In addition, there is increasing evidence that the peroxiredoxins play a role in cell signalling, by controlling and/or sensing hydrogen peroxide and peroxynitrite levels. In this, the first book containing a broad survey on the peroxiredoxins, the editors succeeded to involve almost all groups that contributed significant insights into the emerging field. The diverse biological roles of the new protein family are discussed in the context of other antioxidant systems like those based on heme or selenium catalysis. Finally, related future perspectives, which range from antimicrobial therapy up to the understanding of human development and carcinogenesis, are highlighted. Specifically, the book will be of outstanding interest to researchers who want to understand how micro-organisms, plants and animals cope with oxidative stress and how such stress is recognized and linked to adaptive responses via redox regulation of cellular processes.
650		0	_aMEDICINE.
650		0	_aMEDICAL PARASITOLOGY.
650		0	_aBIOCHEMISTRY.
650		0	_aCYTOLOGY.
650		0	_aMICROBIOLOGY.
650		0	_aBACTERIOLOGY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aPARASITOLOGY.
650	2	4	_aBIOCHEMISTRY, GENERAL.
650	2	4	_aCELL BIOLOGY.
650	2	4	_aMICROBIOLOGY.
650	2	4	_aBACTERIOLOGY.
700	1		_aHarris, J. Robin. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402060502
830		0	_aSubcellular Biochemistry, _x0306-0225 ; _v44
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-6051-9 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c61551 _d61551