000			03528nam a22004815i 4500
001			978-1-4020-6087-8
003			DE-He213
005			20251006084529.0
007			cr nn 008mamaa
008			100301s2008 ne | s |||| 0|eng d
020			_a9781402060878
020			_a99781402060878
024	7		_a10.1007/978-1-4020-6087-8 _2doi
082	0	4	_a614.5999 _223
100	1		_aKaufman, Howard L. _eeditor.
245	1	0	_aGeneral Principles of Tumor Immunotherapy _h[electronic resource] : _bBasic and Clinical Applications of Tumor Immunology / _cedited by Howard L. Kaufman, Jedd D. Wolchok.
264		1	_aDordrecht : _bSpringer Netherlands, _c2008.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aGeneral Principles of Tumor Immunology -- A Perspective on Cancer Immunology and Immunotherapy -- Tumor Antigens -- T Cells and Antigen Recognition -- The Role of Natural Killer T cells in Tumor Immunity -- Immunomodulatory Molecules of the Immune System -- HLA Class I Antigen Abnormalities in Tumors -- The Local Tumor Microenvironment -- Tumor Vaccines -- Peptide and Protein Vaccines for Cancer -- DNA Vaccines Against Cancer -- Recombinant Viral and Bacterial Vaccines -- Dendritic Cell Vaccines -- Whole Cell Vaccines -- Carbohydrate Vaccines Against Cancer -- Passive Immunotherapy Approaches -- Monoclonal Antibody Therapy of Cancer -- Adoptive Cellular Therapy for the Treatment of Cancer -- Checkpoint Blockade and Combinatorial Immunotherapies -- Clinical Tumor Immunotherapy -- General Approaches to Measuring Immune Responses -- Interferon Therapy -- High Dose Interleukin-2 Therapy -- Monoclonal Antibodies in Cancer Therapy -- Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy.
520			_a"General Principles of Tumor Immunotherapy: Basic and Clinical Applications of Tumor Immunology" brings together the world's leading authorities on tumor immunology. This book describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. This information will be invaluable to both students of immunology and cancer research and practicing physicians who have patients with cancer. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aIMMUNOLOGY.
650		0	_aCANCER _xSURGERY.
650	1	4	_aBIOMEDICINE.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aIMMUNOLOGY.
650	2	4	_aONCOLOGY.
650	2	4	_aSURGICAL ONCOLOGY.
650	2	4	_aBIOMEDICINE GENERAL.
700	1		_aWolchok, Jedd D. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402060861
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-6087-8 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c61566 _d61566