000			03010nam a22004455i 4500
001			978-1-4020-6784-6
003			DE-He213
005			20251006084537.0
007			cr nn 008mamaa
008			100301s2008 ne | s |||| 0|eng d
020			_a9781402067846
020			_a99781402067846
024	7		_a10.1007/978-1-4020-6784-6 _2doi
082	0	4	_a614.5999 _223
100	1		_aBunz, Fred. _eauthor.
245	1	0	_aPrinciples of Cancer Genetics _h[electronic resource] / _cby Fred Bunz.
264		1	_aDordrecht : _bSpringer Netherlands, _c2008.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aThe Genetic Basis of Cancer -- Oncogenes -- Tumor Suppressor Genes -- Genetic Instability and Cancer -- Cancer Gene Pathways -- Genetic Alternations in Common Cancers -- Cancer Genetics in the Clinic.
520			_aCancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors. Integrating these disparate pieces of highly specialized information is challenging for the professional scientist and student alike. Prinicples of Cancer Genetics consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. Focused on the most highly representative genes that underlie the most common cancers, Principles of Cancer Genetics is aimed at advanced undergraduates who have completed introductory courses in genetics, biology and biochemistry, medical students, and house medical house staff preparing for board examinations. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand. The many points of controversy in cancer research are avoided, in favor of firmly established concepts. This book does not delve into tumor pathobiology beyond what is required to understand the role of genetic alterations in neoplastic growth. For students with a general interest in cancer, this book will provide a highly accessible overview. For students contemplating future study in the fields of oncology or cancer research, this book will be useful as a primer.
650		0	_aMEDICINE.
650		0	_aONCOLOGY.
650		0	_aHUMAN GENETICS.
650	1	4	_aBIOMEDICINE.
650	2	4	_aCANCER RESEARCH.
650	2	4	_aONCOLOGY.
650	2	4	_aHUMAN GENETICS.
650	2	4	_aBIOMEDICINE GENERAL.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402067839
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-6784-6 _zVer el texto completo en las instalaciones del CICY
912			_aZDB-2-SBL
942			_2ddc _cER
999			_c61859 _d61859