000			02044nam a2200325Ia 4500
003			MX-MdCICY
005			20251009160711.0
040			_cCICY
090			_aB-21975
245	1	0	_aNon-coding RNAs in Cancer: Mechanistic insights and therapeutic implications.
490	0		_aPathology-Research and Practice, 266, 155745, 2025.
500			_aArtículo
520	3		_aNon-coding RNAs have gathered significant attention for their unique roles in biological regulation. Across a broad spectrum of developmental processes and diseases, particularly in human malignancies, ncRNAs play pivotal roles in regulatory mechanisms. MicroRNAs, long noncoding RNAs, and small nucleolar RNAs stand out among the diverse forms of ncRNAs that have been implicated in cancer. MiRNAs, classified as short non-coding RNAs, modulate gene expression by binding to messenger RNA molecules, thereby inhibiting their translation. Altered miRNA expression has been associated with the onset and progression of various malignancies, including lung, breast, and prostate cancer. In contrast, lncRNAs, characterized as longer ncRNAs, exert control over gene expression through various mechanisms, such as chromatin remodelling and gene silencing. This review offers a comprehensive examination of the numerous ncRNAs that have emerged as crucial regulators of gene expression, playing implicated roles in the initiation and progression of diverse cancers.
650	1	4	_aCANCER BIOLOGY
650	1	4	_aMIRNA
650	1	4	_aLNCRNA
650	1	4	_aCIRCRNA
650	1	4	_aCANCER DIAGNOSIS
650	1	4	_aTHERAPEUTIC TARGETS
700	1	2	_aJohn, A.
700	1	2	_aAlmulla, N.
700	1	2	_aElboughdiri, N.
700	1	2	_aGacem, A.
700	1	2	_aYadav, K. K.
700	1	2	_aAbass, A. M.
700	1	2	_aWani, A. K.
856	4	0	_uhttps://drive.google.com/file/d/1N72_v4j00xvWUOEQA79uSzmqSoipvCct/view?usp=drive_link _zPara ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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