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LncRNAs chaperoning dynamic protein condensates in cancer cells.

Tipo de material: TextoTextoSeries Molecular Cell, 84(24), 4695-4697, 2024Trabajos contenidos:
  • Hu, J
  • Li, D
  • Liu, C
Tema(s): Recursos en línea: Resumen: In this issue of Molecular Cell, Sun et al. reveal that the long non-coding RNA (lncRNA) DNAJC3-AS1 plays a dual role in maintaining the rRNA processing function of fibrillarin (FBL) in cancer cells. It promotes FBL condensation while preventing abnormal aggregation, offering new therapeutic insights for cancer treatment by targeting lncRNAs involved in the regulation of FBL condensation.
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Documentos solicitados Documentos solicitados CICY Documento préstamo interbibliotecario Ref1 B-21899 (Browse shelf(Opens below)) Available

Artículo

In this issue of Molecular Cell, Sun et al. reveal that the long non-coding RNA (lncRNA) DNAJC3-AS1 plays a dual role in maintaining the rRNA processing function of fibrillarin (FBL) in cancer cells. It promotes FBL condensation while preventing abnormal aggregation, offering new therapeutic insights for cancer treatment by targeting lncRNAs involved in the regulation of FBL condensation.

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