Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504)isolated from the mangrove plant Aegiceras corniculatum
Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504)isolated from the mangrove plant Aegiceras corniculatum
- Journal of Asian Natural Products Research, 10(8), p.765-770, 2008 .
Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1)and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b ]indol (3)were isolated, together with (2)-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8ahexahydropyrrolo-[2,3-b ]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.
FUSARIUM INCARNATUM
AEGICERAS CORNICULATUM
MANGROVE
PYRROLE ALKALOID
Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1)and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b ]indol (3)were isolated, together with (2)-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8ahexahydropyrrolo-[2,3-b ]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.
FUSARIUM INCARNATUM
AEGICERAS CORNICULATUM
MANGROVE
PYRROLE ALKALOID
