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Pyrrole and indole alkaloids from an endophytic Fusarium incarnatum (HKI00504)isolated from the mangrove plant Aegiceras corniculatum

Tipo de material: TextoTextoSeries ; Journal of Asian Natural Products Research, 10(8), p.765-770, 2008Trabajos contenidos:
  • Li, L.-Y
  • Ding, Y
  • Groth, I
  • Menzel, K.-D
  • Peschel, G
  • Voigt, K
  • Deng, Z.-W
  • Deng, Z.-W
  • Lin, W.-H
Tema(s): Recursos en línea: Resumen: Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1)and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b ]indol (3)were isolated, together with (2)-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8ahexahydropyrrolo-[2,3-b ]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.
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Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1)and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b ]indol (3)were isolated, together with (2)-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8ahexahydropyrrolo-[2,3-b ]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.

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