In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens (Record no. 43560)

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control field MX-MdCICY
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control field 20250625140610.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-9309
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Title In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens
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Volume/sequential designation Bioorganic & Medicinal Chemistry Letters, 18(4), p.1511-1514, 2008
520 3# - SUMMARY, ETC.
Summary, etc. Four flavones, 3,40-O-dimethylquercetin (1), 3,7-O-dimethylquercetin (2), 3-O-methylquercetin (3)and 3,7,40-O-trimethylquercetin (4)were isolated as the inhibitors of nitric oxide production in activated microglia (IC50 values: 11.1, 4.2, 3.8, and 25.1 lM, respectively). They suppressed the expression of protein and mRNA of inducible nitric oxide synthase. Furthermore, compounds 2 and 3 showed scavenging activity of peroxynitrite with SC50 values of 1.75 and 0.77 lM, respectively.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kim, J.Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Lim, H.J.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Ryu, J.H.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1F1ZtMxDXWMmBJBOSbYclL60fTGvw26BS/view?usp=drivesdk">https://drive.google.com/file/d/1F1ZtMxDXWMmBJBOSbYclL60fTGvw26BS/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-9309 25.06.2025 25.06.2025 Documentos solicitados