Influence of additives on melt viscosity, surface tension, and film formation of dry powder coatings (Record no. 46400)

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control field MX-MdCICY
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control field 20250625140705.0
040 ## - CATALOGING SOURCE
Transcribing agency CICY
090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN)
Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12189
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245 10 - TITLE STATEMENT
Title Influence of additives on melt viscosity, surface tension, and film formation of dry powder coatings
490 0# - SERIES STATEMENT
Volume/sequential designation Drug Development and Industrial Pharmacy, 35(6), p.646-654, 2009
520 3# - SUMMARY, ETC.
Summary, etc. Background: Limited information on thermally cured dry-powder coatings used for solid dosage forms has been available in the literature. Aim: The aim of this study was to characterize the film formation process of Eudragit® L 100-55 dry-powder coatings and to investigate the influence of film additives on melt viscosity and surface tension. Methods: The coating process employed no liquids and the plasticizer was combined with the polymer using hot melt extrusion. Thermoanalytical methods including differential scanning calorimetry and thermogravimetric analysis (TGA)were used to investigate the thermal properties of the dry-coating formulations. The rheological behavior of the coating formulations were characterized with the extrusion torque, and the surface energy parameters were determined from contact angle measurements. The influence of the level of triethyl citrate (TEC)as plasticizer and polyethylene glycol (PEG)3350 in the polymer film on film formation was investigated using a digital force tester. Results: TGA confirmed thermal stability of all coating excipients at the investigated curing conditions. Increasing TEC levels and the addition of PEG 3350 as a low melting excipient in the coating reduced the viscosity of the polymer. Plasticization of the polymer with TEC increased the surface free energy, whereas the admixture of 10
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element EUDRAGIT® L 100-55
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element DRY POWDER COATING
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element FILM FORMATION
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MELT VISCOSITY
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element SURFACE FREE ENERGY
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sauer, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Mcginity, J.W.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://drive.google.com/file/d/1HGJWBloRuphBfVDr91yshboZhx9Liliw/view?usp=drivesdk">https://drive.google.com/file/d/1HGJWBloRuphBfVDr91yshboZhx9Liliw/view?usp=drivesdk</a>
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12189 25.06.2025 25.06.2025 Documentos solicitados