Glycerol-3-phosphate is a critical mobile inducer of systemic immunity in plants (Record no. 46884)

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control field MX-MdCICY
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control field 20250625153905.0
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Transcribing agency CICY
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Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) B-12677
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Title Glycerol-3-phosphate is a critical mobile inducer of systemic immunity in plants
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Volume/sequential designation Nature Genetics, 43, p.421-427, 2011
520 3# - SUMMARY, ETC.
Summary, etc. Glycerol-3-phosphate (G3P)is an important metabolite that contributes to the growth and disease-related physiologies of prokaryotes, plants, animals and humans alike. Here we show that G3P serves as the inducer of an important form of broad-spectrum immunity in plants, termed systemic acquired resistance (SAR). SAR is induced upon primary infection and protects distal tissues from secondary infections. Genetic mutants defective in G3P biosynthesis cannot induce SAR but can be rescued when G3P is supplied exogenously. Radioactive tracer experiments show that a G3P derivative is translocated to distal tissues, and this requires the lipid transfer protein, DIR1. Conversely, G3P is required for the translocation of DIR1 to distal tissues, which occurs through the symplast. These observations, along with the fact that dir1 plants accumulate reduced levels of G3P in their petiole exudates, suggest that the cooperative interaction of DIR1 and G3P orchestrates the induction of SAR in plants.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Chanda, B.
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Personal name Xia, Y.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kumar Mandal, M.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Yu, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Sekine, K.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Gao, Q.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Selote, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Selote, D.
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Personal name Stromberg, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Navarre, D.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kachroo, A.
700 12 - ADDED ENTRY--PERSONAL NAME
Personal name Kachroo, P.
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Uniform Resource Identifier <a href="https://drive.google.com/file/d/1I-4ZtXmulXsnTAGrkDUavd4k1HUYth1-/view?usp=drivesdk">https://drive.google.com/file/d/1I-4ZtXmulXsnTAGrkDUavd4k1HUYth1-/view?usp=drivesdk</a>
Public note Para ver el documento ingresa a Google con tu cuenta: @cicy.edu.mx
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Source of classification or shelving scheme Clasificación local
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  Clasificación local     Ref1 CICY CICY Documento préstamo interbibliotecario 25.06.2025   B-12677 25.06.2025 25.06.2025 Documentos solicitados